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Identification of murine gammaherpesvirus 68 miRNA-mRNA hybrids reveals miRNA target conservation among gammaherpesviruses including host translation and protein modification machinery

Gammaherpesviruses, including the human pathogens Epstein-Barr virus (EBV) and Kaposi’s sarcoma-associated herpesvirus (KSHV), establish lifelong latent infection in B cells and are associated with a variety of tumors. In addition to protein coding genes, these viruses encode numerous microRNAs (miR...

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Detalles Bibliográficos
Autores principales: Bullard, Whitney L., Kara, Mehmet, Gay, Lauren A., Sethuraman, Sunantha, Wang, Yiping, Nirmalan, Shreya, Esemenli, Alim, Feswick, April, Hoffman, Brett A., Renne, Rolf, Tibbetts, Scott A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687095/
https://www.ncbi.nlm.nih.gov/pubmed/31393953
http://dx.doi.org/10.1371/journal.ppat.1007843