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In vivo proteomics identifies the competence regulon and AliB oligopeptide transporter as pathogenic factors in pneumococcal meningitis

Streptococcus pneumoniae (pneumococci) is a leading cause of severe bacterial meningitis in many countries worldwide. To characterize the repertoire of fitness and virulence factors predominantly expressed during meningitis we performed niche-specific analysis of the in vivo proteome in a mouse meni...

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Detalles Bibliográficos
Autores principales: Schmidt, Frank, Kakar, Niamatullah, Meyer, Tanja C., Depke, Maren, Masouris, Ilias, Burchhardt, Gerhard, Gómez-Mejia, Alejandro, Dhople, Vishnu, Håvarstein, Leiv S., Sun, Zhi, Moritz, Robert L., Völker, Uwe, Koedel, Uwe, Hammerschmidt, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687184/
https://www.ncbi.nlm.nih.gov/pubmed/31356624
http://dx.doi.org/10.1371/journal.ppat.1007987