Single-Cell RNA Sequencing of Visceral Adipose Tissue Leukocytes Reveals that Caloric Restriction Following Obesity Promotes the Accumulation of a Distinct Macrophage Population with Features of Phagocytic Cells

Obesity can lead to type 2 diabetes and is an epidemic. A major contributor to its adverse effects is inflammation of the visceral adipose tissue (VAT). Life-long caloric restriction (CR), in contrast, results in extended lifespan, enhanced glucose tolerance/insulin sensitivity, and other favorable...

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Detalles Bibliográficos
Autores principales: Weinstock, Ada, Brown, Emily J., Garabedian, Michela L., Pena, Stephanie, Sharma, Monika, Lafaille, Juan, Moore, Kathryn J., Fisher, Edward A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687332/
https://www.ncbi.nlm.nih.gov/pubmed/31396408
http://dx.doi.org/10.20900/immunometab20190008

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