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1,25(OH)(2)D(3) regulates the proangiogenic activity of pericyte through VDR‐mediated modulation of VEGF production and signaling of VEGF and PDGF receptors

We have previously demonstrated that the active form of vitamin D (calcitriol; 1,25(OH)(2)D(3)) is a potent inhibitor of retinal neovascularization. However, the underlying molecular and cellular mechanisms involved remained poorly understood. Perivascular supporting cells including pericytes (PC) p...

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Detalles Bibliográficos
Autores principales: Jamali, Nasim, Song, Yong‐Seok, Sorenson, Christine M., Sheibani, Nader
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687334/
https://www.ncbi.nlm.nih.gov/pubmed/31396585
http://dx.doi.org/10.1096/fba.2018-00067