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Nomogram predicting the likelihood of complications after surgery for deep endometriosis without bowel involvement

STUDY OBJECTIVE: To describe complications following surgery for deep endometriosis (DE) without bowel involvement and to develop a nomogram for predicting postoperative complications. DESIGN: Retrospective study SETTING: Tertiary referral university hospital and expert center in endometriosis PATIE...

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Detalles Bibliográficos
Autores principales: Poupon, Clothilde, Owen, Clémentine, Arfi, Alexandra, Cohen, Jonathan, Bendifallah, Sofiane, Daraï, Emile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687381/
https://www.ncbi.nlm.nih.gov/pubmed/31403118
http://dx.doi.org/10.1016/j.eurox.2019.100028
Descripción
Sumario:STUDY OBJECTIVE: To describe complications following surgery for deep endometriosis (DE) without bowel involvement and to develop a nomogram for predicting postoperative complications. DESIGN: Retrospective study SETTING: Tertiary referral university hospital and expert center in endometriosis PATIENTS: Two-hundred and twenty patients with DE without bowel involvement INTERVENTIONS: Laparoscopic resection for DE without bowel involvement MEASUREMENTS AND MAIN RESULTS: Operative complications were evaluated using the Clavien-Dindo classification. Voiding dysfunction was defined as a need for bladder self-catheterization lasting >1 month. Fifty-three patients (24%) had postoperative complications: 31 (14%) had a Clavien-Dindo grade I—II complication (3 grade I and 28 grade II); 11 (5%) had a grade III complication (2 grade IIIa and 9 grade IIIb); and 11 (5%) had voiding dysfunction. No grade IV—V complications were observed. Age, Enzian classification risk group, and previous surgery for endometriosis were significantly associated with postoperative complications. The predictive model had an AUC of 0.72 (95% CI, 0.70–0.74) before and 0.70 (95% CI, 0.68–72) after bootstrap sample correction. The average difference and maximal difference in predicted and calibrated probabilities of recurrence were 0.023 and 0.089% respectively CONCLUSION: Surgery for DE without bowel resection is associated with a relatively high incidence of voiding dysfunction and postoperative complications mainly corresponding to Clavien-Dindo grade I—II. Age, risk group of Enzian classification, and previous surgery for endometriosis are significantly associated with postoperative complications and voiding dysfunction. Our results allowed us to build a nomogram which can be used to better inform patients about the risk of DE surgery without bowel involvement