Case Series of Cancer-associated Retinopathy (CAR)

Cancer-associated retinopathy (CAR) is a rare paraneoplastic disorder of the retina leading to blindness, associated with multiple cancers. It can lead to rapid progressive visual deterioration with retinal pathology ranging from retinitis pigmentosa to retinal degeneration. It is caused by antibodi...

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Autores principales: Naramala, Srikanth, Ahmad, Jowairiyya, Adapa, Sreedhar, Gavini, Frank, Konala, Venu Madhav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2019
Materias:
Ophthalmology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687430/
https://www.ncbi.nlm.nih.gov/pubmed/31417817
http://dx.doi.org/10.7759/cureus.4872
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author Naramala, Srikanth
Ahmad, Jowairiyya
Adapa, Sreedhar
Gavini, Frank
Konala, Venu Madhav
author_facet Naramala, Srikanth
Ahmad, Jowairiyya
Adapa, Sreedhar
Gavini, Frank
Konala, Venu Madhav
author_sort Naramala, Srikanth
collection PubMed
description Cancer-associated retinopathy (CAR) is a rare paraneoplastic disorder of the retina leading to blindness, associated with multiple cancers. It can lead to rapid progressive visual deterioration with retinal pathology ranging from retinitis pigmentosa to retinal degeneration. It is caused by antibodies directed against retinal antigens. This uncommon syndrome is a remote effect, independent of the primary tumor or metastatic lesion. We describe two cases of CAR, as well as pathophysiology, clinical manifestation, diagnostic criteria, and treatment of cancer-associated retinopathy.
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spelling pubmed-66874302019-08-15 Case Series of Cancer-associated Retinopathy (CAR) Naramala, Srikanth Ahmad, Jowairiyya Adapa, Sreedhar Gavini, Frank Konala, Venu Madhav Cureus Ophthalmology Cancer-associated retinopathy (CAR) is a rare paraneoplastic disorder of the retina leading to blindness, associated with multiple cancers. It can lead to rapid progressive visual deterioration with retinal pathology ranging from retinitis pigmentosa to retinal degeneration. It is caused by antibodies directed against retinal antigens. This uncommon syndrome is a remote effect, independent of the primary tumor or metastatic lesion. We describe two cases of CAR, as well as pathophysiology, clinical manifestation, diagnostic criteria, and treatment of cancer-associated retinopathy. Cureus 2019-06-10 /pmc/articles/PMC6687430/ /pubmed/31417817 http://dx.doi.org/10.7759/cureus.4872 Text en Copyright © 2019, Naramala et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Ophthalmology
Naramala, Srikanth
Ahmad, Jowairiyya
Adapa, Sreedhar
Gavini, Frank
Konala, Venu Madhav
Case Series of Cancer-associated Retinopathy (CAR)
title Case Series of Cancer-associated Retinopathy (CAR)
title_full Case Series of Cancer-associated Retinopathy (CAR)
title_fullStr Case Series of Cancer-associated Retinopathy (CAR)
title_full_unstemmed Case Series of Cancer-associated Retinopathy (CAR)
title_short Case Series of Cancer-associated Retinopathy (CAR)
title_sort case series of cancer-associated retinopathy (car)
topic Ophthalmology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687430/
https://www.ncbi.nlm.nih.gov/pubmed/31417817
http://dx.doi.org/10.7759/cureus.4872
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