Cargando…

Polycystic ovary syndrome (PCOS) and genetic predisposition: A review article

Polycystic ovary syndrome (PCOS) is a heterogeneous condition which is related to an endocrine reproductive disorder of females. It affects females of 18–44 age. The persistent hormonal disbalance leads to the complexities such as numerous cysts, an irregular menstrual cycle that ultimately leads to...

Descripción completa

Detalles Bibliográficos
Autores principales: Ajmal, Nida, Khan, Sanam Zeib, Shaikh, Rozeena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687436/
https://www.ncbi.nlm.nih.gov/pubmed/31403134
http://dx.doi.org/10.1016/j.eurox.2019.100060
_version_ 1783442731407769600
author Ajmal, Nida
Khan, Sanam Zeib
Shaikh, Rozeena
author_facet Ajmal, Nida
Khan, Sanam Zeib
Shaikh, Rozeena
author_sort Ajmal, Nida
collection PubMed
description Polycystic ovary syndrome (PCOS) is a heterogeneous condition which is related to an endocrine reproductive disorder of females. It affects females of 18–44 age. The persistent hormonal disbalance leads to the complexities such as numerous cysts, an irregular menstrual cycle that ultimately leads to infertility among females. Many candidate genes have been identified to be one of the causes of PCOS. Different studies have been carried out to find the genetic correlation of PCOS. It is essential to carry out such studies that identify the clear cause of PCOS and its genetic association and hormonal disbalance. This review has highlighted different genes and their correlation with PCOS that leads to hormonal disbalance. Yet not in-depth but an attempt to study the genetic predisposition of PCOS.
format Online
Article
Text
id pubmed-6687436
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-66874362019-08-09 Polycystic ovary syndrome (PCOS) and genetic predisposition: A review article Ajmal, Nida Khan, Sanam Zeib Shaikh, Rozeena Eur J Obstet Gynecol Reprod Biol X Review Polycystic ovary syndrome (PCOS) is a heterogeneous condition which is related to an endocrine reproductive disorder of females. It affects females of 18–44 age. The persistent hormonal disbalance leads to the complexities such as numerous cysts, an irregular menstrual cycle that ultimately leads to infertility among females. Many candidate genes have been identified to be one of the causes of PCOS. Different studies have been carried out to find the genetic correlation of PCOS. It is essential to carry out such studies that identify the clear cause of PCOS and its genetic association and hormonal disbalance. This review has highlighted different genes and their correlation with PCOS that leads to hormonal disbalance. Yet not in-depth but an attempt to study the genetic predisposition of PCOS. Elsevier 2019-06-08 /pmc/articles/PMC6687436/ /pubmed/31403134 http://dx.doi.org/10.1016/j.eurox.2019.100060 Text en © 2019 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review
Ajmal, Nida
Khan, Sanam Zeib
Shaikh, Rozeena
Polycystic ovary syndrome (PCOS) and genetic predisposition: A review article
title Polycystic ovary syndrome (PCOS) and genetic predisposition: A review article
title_full Polycystic ovary syndrome (PCOS) and genetic predisposition: A review article
title_fullStr Polycystic ovary syndrome (PCOS) and genetic predisposition: A review article
title_full_unstemmed Polycystic ovary syndrome (PCOS) and genetic predisposition: A review article
title_short Polycystic ovary syndrome (PCOS) and genetic predisposition: A review article
title_sort polycystic ovary syndrome (pcos) and genetic predisposition: a review article
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687436/
https://www.ncbi.nlm.nih.gov/pubmed/31403134
http://dx.doi.org/10.1016/j.eurox.2019.100060
work_keys_str_mv AT ajmalnida polycysticovarysyndromepcosandgeneticpredispositionareviewarticle
AT khansanamzeib polycysticovarysyndromepcosandgeneticpredispositionareviewarticle
AT shaikhrozeena polycysticovarysyndromepcosandgeneticpredispositionareviewarticle