S100A9-induced overexpression of PD-1/PD-L1 contributes to ineffective hematopoiesis in myelodysplastic syndromes

Myelodysplastic syndromes (MDS) are characterized by dysplastic and ineffective hematopoiesis that can result from aberrant expansion and activation of myeloid-derived suppressor cells (MDSCs) within the bone marrow (BM) niche. MDSCs produce S100A9, which mediates premature death of hematopoietic st...

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Detalles Bibliográficos
Autores principales: Cheng, Pinyang, Eksioglu, Erika A., Chen, Xianghong, Kandell, Wendy, Le Trinh, Thu, Cen, Ling, Qi, Jin, Sallman, David A., Zhang, Yu, Tu, Nhan, Adams, William A., Zhang, Chunze, Liu, Jinhong, Cleveland, John L., List, Alan F., Wei, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687540/
https://www.ncbi.nlm.nih.gov/pubmed/30737486
http://dx.doi.org/10.1038/s41375-019-0397-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687540/
https://www.ncbi.nlm.nih.gov/pubmed/30737486
http://dx.doi.org/10.1038/s41375-019-0397-9

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