Genetic mechanisms of primary chemotherapy resistance in pediatric acute myeloid leukemia

Acute myeloid leukemias (AML) are characterized by mutations of tumor suppressor and oncogenes, involving distinct genes in adults and children. While certain mutations have been associated with the increased risk of AML relapse, the genomic landscape of primary chemotherapy resistant AML is not wel...

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Detalles Bibliográficos
Autores principales: McNeer, Nicole A., Philip, John, Geiger, Heather, Ries, Rhonda E., Lavallée, Vincent-Philippe, Walsh, Michael, Shah, Minita, Arora, Kanika, Emde, Anne-Katrin, Robine, Nicolas, Alonzo, Todd A, Kolb, E. Anders, Gamis, Alan S, Smith, Malcolm, Gerhard, Daniela Se, Guidry-Auvil, Jaime, Meshinchi, Soheil, Kentsis, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687545/
https://www.ncbi.nlm.nih.gov/pubmed/30760869
http://dx.doi.org/10.1038/s41375-019-0402-3

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