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The mechanistic study behind suppression of GVHD while retaining GVL activities by myeloid-derived suppressor cells.

Graft-versus-host disease (GVHD) is a major barrier to the widespread use of allogeneic hematopoietic stem cell transplantation (allo-HSCT) for treating hematologic malignancies. Myeloid-derived suppressor cells (MDSCs) have been recognized as crucial immunosuppressive cells in various pathologic se...

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Detalles Bibliográficos
Autores principales: Zhang, Jilu, Chen, Hui-Ming, Ma, Ge, Zhou, Zuping, Raulet, David, Rivera, Andreana L., Chen, Shu-Hsia, Pan, Ping-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687551/
https://www.ncbi.nlm.nih.gov/pubmed/30737483
http://dx.doi.org/10.1038/s41375-019-0394-z