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The mechanistic study behind suppression of GVHD while retaining GVL activities by myeloid-derived suppressor cells.
Graft-versus-host disease (GVHD) is a major barrier to the widespread use of allogeneic hematopoietic stem cell transplantation (allo-HSCT) for treating hematologic malignancies. Myeloid-derived suppressor cells (MDSCs) have been recognized as crucial immunosuppressive cells in various pathologic se...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687551/ https://www.ncbi.nlm.nih.gov/pubmed/30737483 http://dx.doi.org/10.1038/s41375-019-0394-z |