Cargando…

Comorbidity and retirement in cervical dystonia

BACKGROUND: Cervical dystonia (CD) is the most common form of dystonia. The onset of CD is usually before 60 years of age and it may cause severe functional and psychosocial impairment in everyday life. Recently non-motor symptoms have been reported to occur in CD substantially affecting the quality...

Descripción completa

Detalles Bibliográficos
Autores principales: Ortiz, Rebekka M., Scheperjans, Filip, Mertsalmi, Tuomas, Pekkonen, Eero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687683/
https://www.ncbi.nlm.nih.gov/pubmed/31152297
http://dx.doi.org/10.1007/s00415-019-09402-0
_version_ 1783442755719004160
author Ortiz, Rebekka M.
Scheperjans, Filip
Mertsalmi, Tuomas
Pekkonen, Eero
author_facet Ortiz, Rebekka M.
Scheperjans, Filip
Mertsalmi, Tuomas
Pekkonen, Eero
author_sort Ortiz, Rebekka M.
collection PubMed
description BACKGROUND: Cervical dystonia (CD) is the most common form of dystonia. The onset of CD is usually before 60 years of age and it may cause severe functional and psychosocial impairment in everyday life. Recently non-motor symptoms have been reported to occur in CD substantially affecting the quality of life. METHODS/PATIENTS: We studied comorbidities of patients with primary focal CD in Finland based on ICD-10 codes obtained from the care registry and patient records of 937 confirmed adult isolated focal CD patients between the years 2007–2016. The retirement months and diagnosis of retirement were calculated from pension registry information. The results were compared with 3746 age and gender-matched controls. RESULTS: Most prominent comorbidities with primary focal CD were depression (14%), anxiety (7%), and back pain (11%). The retirement age was significantly younger in CD patients compared to control group controls (59.0 years, 95% CI 58.5–59.5 vs. 61.7 years, 95% CI 61.6–61.9) years, p < 0.001). For dystonia patients the most common diagnoses for retirement due to sickness were dystonia (51%), depression (14%), and anxiety (8%). Patients with anxiety and depression retired earlier than other dystonia patients. DISCUSSION: Cervical dystonia considerably reduces working ability and leads to earlier retirement. Anxiety and depression are most notable comorbidities and their co-occurrence further reduces working ability. Our results suggest that more health care resources should be administered in treatment of CD to longer maintain working ability of CD patients. Further, psychiatric comorbidities should be taken into consideration in CD treatment.
format Online
Article
Text
id pubmed-6687683
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Springer Berlin Heidelberg
record_format MEDLINE/PubMed
spelling pubmed-66876832019-08-23 Comorbidity and retirement in cervical dystonia Ortiz, Rebekka M. Scheperjans, Filip Mertsalmi, Tuomas Pekkonen, Eero J Neurol Original Communication BACKGROUND: Cervical dystonia (CD) is the most common form of dystonia. The onset of CD is usually before 60 years of age and it may cause severe functional and psychosocial impairment in everyday life. Recently non-motor symptoms have been reported to occur in CD substantially affecting the quality of life. METHODS/PATIENTS: We studied comorbidities of patients with primary focal CD in Finland based on ICD-10 codes obtained from the care registry and patient records of 937 confirmed adult isolated focal CD patients between the years 2007–2016. The retirement months and diagnosis of retirement were calculated from pension registry information. The results were compared with 3746 age and gender-matched controls. RESULTS: Most prominent comorbidities with primary focal CD were depression (14%), anxiety (7%), and back pain (11%). The retirement age was significantly younger in CD patients compared to control group controls (59.0 years, 95% CI 58.5–59.5 vs. 61.7 years, 95% CI 61.6–61.9) years, p < 0.001). For dystonia patients the most common diagnoses for retirement due to sickness were dystonia (51%), depression (14%), and anxiety (8%). Patients with anxiety and depression retired earlier than other dystonia patients. DISCUSSION: Cervical dystonia considerably reduces working ability and leads to earlier retirement. Anxiety and depression are most notable comorbidities and their co-occurrence further reduces working ability. Our results suggest that more health care resources should be administered in treatment of CD to longer maintain working ability of CD patients. Further, psychiatric comorbidities should be taken into consideration in CD treatment. Springer Berlin Heidelberg 2019-05-31 2019 /pmc/articles/PMC6687683/ /pubmed/31152297 http://dx.doi.org/10.1007/s00415-019-09402-0 Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Original Communication
Ortiz, Rebekka M.
Scheperjans, Filip
Mertsalmi, Tuomas
Pekkonen, Eero
Comorbidity and retirement in cervical dystonia
title Comorbidity and retirement in cervical dystonia
title_full Comorbidity and retirement in cervical dystonia
title_fullStr Comorbidity and retirement in cervical dystonia
title_full_unstemmed Comorbidity and retirement in cervical dystonia
title_short Comorbidity and retirement in cervical dystonia
title_sort comorbidity and retirement in cervical dystonia
topic Original Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687683/
https://www.ncbi.nlm.nih.gov/pubmed/31152297
http://dx.doi.org/10.1007/s00415-019-09402-0
work_keys_str_mv AT ortizrebekkam comorbidityandretirementincervicaldystonia
AT scheperjansfilip comorbidityandretirementincervicaldystonia
AT mertsalmituomas comorbidityandretirementincervicaldystonia
AT pekkoneneero comorbidityandretirementincervicaldystonia