Cargando…

Correlation between early dynamics in circulating tumour DNA and outcome from FOLFIRI treatment in metastatic colorectal cancer

Chemotherapy resistance remains a challenge in the clinical management of metastatic colorectal cancer (mCRC). Here, early changes in cell-free circulating tumour DNA (ctDNA) levels were explored as a marker of therapeutic efficacy. Twenty-four mCRC patients were enrolled and treated with FOLFIRI ba...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lyskjær, Iben, Kronborg, Camilla Skovhus, Rasmussen, Mads Heilskov, Sørensen, Boe Sandahl, Demuth, Christina, Rosenkilde, Mona, Johansen, Amanda Frydendahl Boll, Knudsen, Michael, Vang, Søren, Krag, Søren Rasmus Palmelund, Spindler, Karen-Lise Garm, Andersen, Claus Lindbjerg
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687711/ https://www.ncbi.nlm.nih.gov/pubmed/31395942 http://dx.doi.org/10.1038/s41598-019-47708-1

Ejemplares similares

Circulating tumor DNA for prognosis assessment and postoperative management after curative‐intent resection of colorectal liver metastases
por: Reinert, Thomas, et al.
Publicado: (2022)

Validation of computational determination of microsatellite status using whole exome sequencing data from colorectal cancer patients
por: Johansen, Amanda Frydendahl Boll, et al.
Publicado: (2019)

Measuring KRAS Mutations in Circulating Tumor DNA by Droplet Digital PCR and Next-Generation Sequencing
por: Demuth, Christina, et al.
Publicado: (2018)

Analysis of Plasma Cell-Free DNA by Ultradeep Sequencing in Patients With Stages I to III Colorectal Cancer
por: Reinert, Thomas, et al.
Publicado: (2019)

DREAMS: deep read-level error model for sequencing data applied to low-frequency variant calling and circulating tumor DNA detection
por: Christensen, Mikkel H., et al.
Publicado: (2023)

Circulating cell-free DNA as predictor of pathological complete response in locally advanced rectal cancer patients undergoing preoperative chemoradiotherapy
por: Truelsen, Christina Glismand, et al.
Publicado: (2022)

Nonplatinum‐based therapy with Paclitaxel and Capecitabine for advanced squamous cell carcinomas of the anal canal: A population‐based Danish anal cancer group study
por: Truelsen, Christina Glismand, et al.
Publicado: (2021)

miR-625-3p regulates oxaliplatin resistance by targeting MAP2K6-p38 signalling in human colorectal adenocarcinoma cells
por: Rasmussen, Mads Heilskov, et al.
Publicado: (2016)

Tumour blood flow for prediction of human prostate cancer aggressiveness: a study with Rubidium-82 PET, MRI and Na(+)/K(+)-ATPase-density
por: Jochumsen, Mads Ryø, et al.
Publicado: (2020)

Comparing single‐target and multitarget approaches for postoperative circulating tumour DNA detection in stage II–III colorectal cancer patients
por: Henriksen, Tenna Vesterman, et al.
Publicado: (2022)

Longitudinal tracking of acute kidney injury reveals injury propagation along the nephron
por: Bordoni, Luca, et al.
Publicado: (2023)

The Clinical Value of Measuring Circulating HPV DNA during Chemo-Radiotherapy in Squamous Cell Carcinoma of the Anus
por: Lefèvre, Anna C., et al.
Publicado: (2021)

Impact of Whole Genome Doubling on Detection of Circulating Tumor DNA in Colorectal Cancer
por: Kabel, Jonas, et al.
Publicado: (2023)

Analysis of circulating tumor DNA during checkpoint inhibition in metastatic melanoma using a tumor-agnostic panel
por: Kisistók, Judit, et al.
Publicado: (2023)

Estimated dose to site of loco-regional recurrence after radiotherapy in anal cancer using point of origin methods
por: Lycke Wind, Karen, et al.
Publicado: (2023)

Disease Control With FOLFIRI Plus Ziv-aflibercept (zFOLFIRI) Beyond FOLFIRI Plus Bevacizumab: Case Series in Metastatic Colorectal Cancer (mCRC)
por: El-Deiry, Wafik S., et al.
Publicado: (2019)

Balanitis associated with FOLFIRI chemotherapy
por: Micevic, Goran, et al.
Publicado: (2017)

A method for treatment monitoring using circulating tumour DNA in cancer patients without targetable mutations
por: Demuth, Christina, et al.
Publicado: (2018)

Testing Danegaptide Effects on Kidney Function after Ischemia/Reperfusion Injury in a New Porcine Two Week Model
por: Amdisen, Chris, et al.
Publicado: (2016)

Pelvic Insufficiency Fractures and Bone Pain after Radiation Therapy for Anal Cancer: Relation to Pelvic Bone Dose-Volume Parameters
por: Kronborg, Camilla Jensenius, et al.
Publicado: (2022)

The potential role of Alu Y in the development of resistance to SN38 (Irinotecan) or oxaliplatin in colorectal cancer
por: Lin, Xue, et al.
Publicado: (2015)

Dasatinib and Doxorubicin Treatment of Sarcoma Initiating Cells: A Possible New Treatment Strategy
por: Aggerholm-Pedersen, Ninna, et al.
Publicado: (2016)

The T790M resistance mutation in EGFR is only found in cfDNA from erlotinib-treated NSCLC patients that harbored an activating EGFR mutation before treatment
por: Demuth, Christina, et al.
Publicado: (2018)

Increased PD-L1 expression in erlotinib-resistant NSCLC cells with MET gene amplification is reversed upon MET-TKI treatment
por: Demuth, Christina, et al.
Publicado: (2017)

Efficacy and safety of FOLFIRI and biotherapy versus FOLFIRI alone for metastatic colorectal cancer patients: A meta-analysis
por: Jiang, Yangbo, et al.
Publicado: (2017)

Drug Trafficking into Macrophages via the Endocytotic Receptor CD163
por: Graversen, Jonas Heilskov, et al.
Publicado: (2015)

Folfiri-Aflibercept vs. Folfiri-Bevacizumab as Second Line Treatment of RAS Mutated Metastatic Colorectal Cancer in Real Practice
por: Ottaiano, Alessandro, et al.
Publicado: (2019)

Novel DNA methylation biomarkers show high sensitivity and specificity for blood-based detection of colorectal cancer—a clinical biomarker discovery and validation study
por: Jensen, Sarah Østrup, et al.
Publicado: (2019)

Breast cancer: comparison of quantitative dual-layer spectral CT and axillary ultrasonography for preoperative diagnosis of metastatic axillary lymph nodes
por: Buus, Thomas Winther, et al.
Publicado: (2021)

Circulating tumor DNA: Response Evaluation Criteria in Solid Tumors – can we RECIST? Focus on colorectal cancer
por: Spindler, Karen-Lise Garm, et al.
Publicado: (2023)

A genetically inducible porcine model of intestinal cancer
por: Callesen, Morten M., et al.
Publicado: (2017)

Correlation between circulating mutant DNA and metabolic tumour burden in advanced non-small cell lung cancer patients
por: Winther-Larsen, Anne, et al.
Publicado: (2017)

Intensified Induction Chemotherapy in Locally Advanced Squamous Cell Carcinoma of the Anus—A Population-Based Experience from the Danish Anal Cancer Group
por: Wind, Karen Lycke, et al.
Publicado: (2021)

Mean overall survival gain with aflibercept plus FOLFIRI vs placebo plus FOLFIRI in patients with previously treated metastatic colorectal cancer
por: Joulain, F, et al.
Publicado: (2013)

A phase 2 randomised study of veliparib plus FOLFIRI±bevacizumab versus placebo plus FOLFIRI±bevacizumab in metastatic colorectal cancer
por: Gorbunova, Vera, et al.
Publicado: (2018)

A Case of Organizing Pneumonia Associated with FOLFIRI Chemotherapy
por: Lee, Yoon Jeong, et al.
Publicado: (2014)

Circular stable intronic RNAs possess distinct biological features and are deregulated in bladder cancer
por: Rasmussen, Asta M, et al.
Publicado: (2023)

Correction: A phase 2 randomised study of veliparib plus FOLFIRI±bevacizumab versus placebo plus FOLFIRI±bevacizumab in metastatic colorectal cancer
por: Gorbunova, Vera, et al.
Publicado: (2019)

Spot-scanning proton therapy for targets with adjacent cardiac implantable electronic devices – Strategies for breast and head & neck cancer
por: Stick, Line Bjerregaard, et al.
Publicado: (2022)

Targeting of CD163(+) Macrophages in Inflammatory and Malignant Diseases
por: Skytthe, Maria K., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_edeu06lvguj5p2neh6k7juq179