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Folate can promote the methionine-dependent reprogramming of glioblastoma cells towards pluripotency

Methionine dependency of tumor growth, although not well-understood, is detectable by (11)C-methionine positron emission tomography and may contribute to the aggressivity of glioblastomas (GBM) and meningiomas. Cytosolic folate cycle is required for methionine synthesis. Its dysregulation may influe...

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Detalles Bibliográficos
Autores principales:	Zgheib, Racha, Battaglia-Hsu, Shyue-Fang, Hergalant, Sébastien, Quéré, Maelle, Alberto, Jean-Marc, Chéry, Céline, Rouyer, Pierre, Gauchotte, Guillaume, Guéant, Jean-Louis, Namour, Farès
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687714/ https://www.ncbi.nlm.nih.gov/pubmed/31395852 http://dx.doi.org/10.1038/s41419-019-1836-2

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