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Bis-naphthopyrone pigments protect filamentous ascomycetes from a wide range of predators
It is thought that fungi protect themselves from predation by the production of compounds that are toxic to soil-dwelling animals. Here, we show that a nontoxic pigment, the bis-naphthopyrone aurofusarin, protects Fusarium fungi from a wide range of animal predators. We find that springtails (primit...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687722/ https://www.ncbi.nlm.nih.gov/pubmed/31395863 http://dx.doi.org/10.1038/s41467-019-11377-5 |
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author | Xu, Yang Vinas, Maria Alsarrag, Albatol Su, Ling Pfohl, Katharina Rohlfs, Marko Schäfer, Wilhelm Chen, Wei Karlovsky, Petr |
author_facet | Xu, Yang Vinas, Maria Alsarrag, Albatol Su, Ling Pfohl, Katharina Rohlfs, Marko Schäfer, Wilhelm Chen, Wei Karlovsky, Petr |
author_sort | Xu, Yang |
collection | PubMed |
description | It is thought that fungi protect themselves from predation by the production of compounds that are toxic to soil-dwelling animals. Here, we show that a nontoxic pigment, the bis-naphthopyrone aurofusarin, protects Fusarium fungi from a wide range of animal predators. We find that springtails (primitive hexapods), woodlice (crustaceans), and mealworms (insects) prefer feeding on fungi with disrupted aurofusarin synthesis, and mealworms and springtails are repelled by wheat flour amended with the fungal bis-naphthopyrones aurofusarin, viomellein, or xanthomegnin. Predation stimulates aurofusarin synthesis in several Fusarium species and viomellein synthesis in Aspergillus ochraceus. Aurofusarin displays low toxicity in mealworms, springtails, isopods, Drosophila, and insect cells, contradicting the common view that fungal defence metabolites are toxic. Our results indicate that bis-naphthopyrones are defence compounds that protect filamentous ascomycetes from predators through a mechanism that does not involve toxicity. |
format | Online Article Text |
id | pubmed-6687722 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-66877222019-08-12 Bis-naphthopyrone pigments protect filamentous ascomycetes from a wide range of predators Xu, Yang Vinas, Maria Alsarrag, Albatol Su, Ling Pfohl, Katharina Rohlfs, Marko Schäfer, Wilhelm Chen, Wei Karlovsky, Petr Nat Commun Article It is thought that fungi protect themselves from predation by the production of compounds that are toxic to soil-dwelling animals. Here, we show that a nontoxic pigment, the bis-naphthopyrone aurofusarin, protects Fusarium fungi from a wide range of animal predators. We find that springtails (primitive hexapods), woodlice (crustaceans), and mealworms (insects) prefer feeding on fungi with disrupted aurofusarin synthesis, and mealworms and springtails are repelled by wheat flour amended with the fungal bis-naphthopyrones aurofusarin, viomellein, or xanthomegnin. Predation stimulates aurofusarin synthesis in several Fusarium species and viomellein synthesis in Aspergillus ochraceus. Aurofusarin displays low toxicity in mealworms, springtails, isopods, Drosophila, and insect cells, contradicting the common view that fungal defence metabolites are toxic. Our results indicate that bis-naphthopyrones are defence compounds that protect filamentous ascomycetes from predators through a mechanism that does not involve toxicity. Nature Publishing Group UK 2019-08-08 /pmc/articles/PMC6687722/ /pubmed/31395863 http://dx.doi.org/10.1038/s41467-019-11377-5 Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Xu, Yang Vinas, Maria Alsarrag, Albatol Su, Ling Pfohl, Katharina Rohlfs, Marko Schäfer, Wilhelm Chen, Wei Karlovsky, Petr Bis-naphthopyrone pigments protect filamentous ascomycetes from a wide range of predators |
title | Bis-naphthopyrone pigments protect filamentous ascomycetes from a wide range of predators |
title_full | Bis-naphthopyrone pigments protect filamentous ascomycetes from a wide range of predators |
title_fullStr | Bis-naphthopyrone pigments protect filamentous ascomycetes from a wide range of predators |
title_full_unstemmed | Bis-naphthopyrone pigments protect filamentous ascomycetes from a wide range of predators |
title_short | Bis-naphthopyrone pigments protect filamentous ascomycetes from a wide range of predators |
title_sort | bis-naphthopyrone pigments protect filamentous ascomycetes from a wide range of predators |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687722/ https://www.ncbi.nlm.nih.gov/pubmed/31395863 http://dx.doi.org/10.1038/s41467-019-11377-5 |
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