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Keap1/Nrf2 Signaling: A New Player in Thyroid Pathophysiology and Thyroid Cancer

The Keap1/Nrf2 pathway is a key mediator of general redox and tissue-specific homeostasis. It also exerts a dual role in cancer, by preventing cell transformation of normal cells but promoting aggressiveness, and drug resistance of malignant ones. Although Nrf2 is well-studied in other tissues, its...

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Detalles Bibliográficos
Autores principales: Renaud, Cedric O., Ziros, Panos G., Chartoumpekis, Dionysios V., Bongiovanni, Massimo, Sykiotis, Gerasimos P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687762/
https://www.ncbi.nlm.nih.gov/pubmed/31428048
http://dx.doi.org/10.3389/fendo.2019.00510