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Keap1/Nrf2 Signaling: A New Player in Thyroid Pathophysiology and Thyroid Cancer
The Keap1/Nrf2 pathway is a key mediator of general redox and tissue-specific homeostasis. It also exerts a dual role in cancer, by preventing cell transformation of normal cells but promoting aggressiveness, and drug resistance of malignant ones. Although Nrf2 is well-studied in other tissues, its...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687762/ https://www.ncbi.nlm.nih.gov/pubmed/31428048 http://dx.doi.org/10.3389/fendo.2019.00510 |