Field cancerization therapy with ingenol mebutate contributes to restoring skin-metabolism to normal-state in patients with actinic keratosis: a metabolomic analysis

Actinic keratosis (AK) is a skin premalignant lesion, which progresses into squamous cell carcinoma (SCC) if left untreated. Ingenol mebutate gel is approved for local treatment of non-hyperkeratotic, non-hypertrophic AK; it also has the potential to act as a field cancerization therapy to prevent t...

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Detalles Bibliográficos
Autores principales: Righi, Valeria, Tarentini, Elisabetta, Mucci, Adele, Reggiani, Camilla, Rossi, Maria Cecilia, Ferrari, Federica, Casari, Alice, Magnoni, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687779/
https://www.ncbi.nlm.nih.gov/pubmed/31395965
http://dx.doi.org/10.1038/s41598-019-47984-x

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