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PUM1 knockdown prevents tumor progression by activating the PERK/eIF2/ATF4 signaling pathway in pancreatic adenocarcinoma cells

Pancreatic ductal adenocarcinoma (PDAC) is a malignant tumor with very poor prognosis. Therefore, it is important to fully understand the molecular mechanism underlying its occurrence and development. Pumilio RNA-binding family member 1 (PUM1) has been reported to function as an oncogene in ovarian...

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Detalles Bibliográficos
Autores principales:	Dai, Haisu, Shen, Kaicheng, Yang, Yishi, Su, Xingxing, Luo, Yuandeng, Jiang, Yan, Shuai, Ling, Zheng, Ping, Chen, Zhiyu, Bie, Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687830/ https://www.ncbi.nlm.nih.gov/pubmed/31395860 http://dx.doi.org/10.1038/s41419-019-1839-z

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