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Early Transcriptional Signature in Dendritic Cells and the Induction of Protective T Cell Responses Upon Immunization With VLPs Containing TLR Ligands—A Role for CCL2
Inducing T cell responses by therapeutic vaccination requires appropriate activation of antigen presenting cells (APCs). The use of virus-like particles (VLPs) containing Toll-like receptor (TLR) ligands has demonstrated remarkable potential in activating APCs and modulating the immune response both...
Autores principales: | Gomes, Ariane C., Mohsen, Mona O., Mueller, Julius E., Leoratti, Fabiana M. S., Cabral-Miranda, Gustavo, Bachmann, Martin F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687836/ https://www.ncbi.nlm.nih.gov/pubmed/31428084 http://dx.doi.org/10.3389/fimmu.2019.01679 |
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