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Computer simulations of food oral processing to engineer teeth cleaning
Oral biofilm accumulation in pets is a growing concern. It is desirable to address this problem via non-invasive teeth cleaning techniques, such as through friction between teeth and food during chewing. Therefore, pet food design tools are needed towards optimising cleaning efficacy. Developing suc...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687884/ https://www.ncbi.nlm.nih.gov/pubmed/31395864 http://dx.doi.org/10.1038/s41467-019-11288-5 |
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author | Skamniotis, C. G. Elliott, M. Charalambides, M. N. |
author_facet | Skamniotis, C. G. Elliott, M. Charalambides, M. N. |
author_sort | Skamniotis, C. G. |
collection | PubMed |
description | Oral biofilm accumulation in pets is a growing concern. It is desirable to address this problem via non-invasive teeth cleaning techniques, such as through friction between teeth and food during chewing. Therefore, pet food design tools are needed towards optimising cleaning efficacy. Developing such tools is challenging, as several parameters affecting teeth cleaning should be considered: the food’s complex mechanical response, the contacting surfaces topology as well as the wide range of masticatory and anatomical characteristics amongst breeds. We show that Finite Element (FE) models can efficiently account for all these parameters, through the simulation of food deformation and fracture during the first bite. This reduces the need for time consuming and costly in-vivo or in-vitro trials. Our in-silico model is validated through in-vitro tests, demonstrating that the initial oral processing stage can be engineered through computers with high fidelity. |
format | Online Article Text |
id | pubmed-6687884 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-66878842019-08-12 Computer simulations of food oral processing to engineer teeth cleaning Skamniotis, C. G. Elliott, M. Charalambides, M. N. Nat Commun Article Oral biofilm accumulation in pets is a growing concern. It is desirable to address this problem via non-invasive teeth cleaning techniques, such as through friction between teeth and food during chewing. Therefore, pet food design tools are needed towards optimising cleaning efficacy. Developing such tools is challenging, as several parameters affecting teeth cleaning should be considered: the food’s complex mechanical response, the contacting surfaces topology as well as the wide range of masticatory and anatomical characteristics amongst breeds. We show that Finite Element (FE) models can efficiently account for all these parameters, through the simulation of food deformation and fracture during the first bite. This reduces the need for time consuming and costly in-vivo or in-vitro trials. Our in-silico model is validated through in-vitro tests, demonstrating that the initial oral processing stage can be engineered through computers with high fidelity. Nature Publishing Group UK 2019-08-08 /pmc/articles/PMC6687884/ /pubmed/31395864 http://dx.doi.org/10.1038/s41467-019-11288-5 Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Skamniotis, C. G. Elliott, M. Charalambides, M. N. Computer simulations of food oral processing to engineer teeth cleaning |
title | Computer simulations of food oral processing to engineer teeth cleaning |
title_full | Computer simulations of food oral processing to engineer teeth cleaning |
title_fullStr | Computer simulations of food oral processing to engineer teeth cleaning |
title_full_unstemmed | Computer simulations of food oral processing to engineer teeth cleaning |
title_short | Computer simulations of food oral processing to engineer teeth cleaning |
title_sort | computer simulations of food oral processing to engineer teeth cleaning |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687884/ https://www.ncbi.nlm.nih.gov/pubmed/31395864 http://dx.doi.org/10.1038/s41467-019-11288-5 |
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