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Delivery of Antigen to CD8(+) Dendritic Cells by Fusing Antigen With Formyl Peptide Receptor-Like 1 Inhibitor Protein Induces Antitumor Immunity
A major challenge for vaccine development is targeting antigens to dendritic cells (DCs) in vivo, enabling cross-presentation, and inducing the memory responses. Fcγ receptors (FcγRs) are expressed on many cell types including DCs. Therefore, targeting of antigen to DCs via FcγRs is an attractive st...
Autores principales: | Chiang, Chen-Yi, Wu, Chiao-Chieh, Chen, Yi-Jyun, Liu, Shih-Jen, Leng, Chih-Hsiang, Chen, Hsin-Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688046/ https://www.ncbi.nlm.nih.gov/pubmed/31428106 http://dx.doi.org/10.3389/fimmu.2019.01839 |
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