Cargando…

Immunomodulatory asthma therapy in the equine animal model: A dose‐response study and evaluation of a long‐term effect

INTRODUCTION: Equine asthma represents a naturally occurring animal model for human allergic neutrophilic asthma. Inhalative nanoparticle‐bound cytosine‐phosphate‐guanosine (CpG‐GNP) immunotherapy, independent of specific allergens, has already shown promising clinical and immunological results in p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Klier, John, Bartl, Carolin, Geuder, Sabine, Geh, Katharina J., Reese, Sven, Goehring, Lutz S., Winter, Gerhard, Gehlen, Heidrun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688086/ https://www.ncbi.nlm.nih.gov/pubmed/31141308 http://dx.doi.org/10.1002/iid3.252

Ejemplares similares

A comparison of nanoparticullate CpG immunotherapy with and without allergens in spontaneously equine asthma‐affected horses, an animal model
por: Klier, John, et al.
Publicado: (2017)

Inhalative Nanoparticulate CpG Immunotherapy in Severe Equine Asthma: An Innovative Therapeutic Concept and Potential Animal Model for Human Asthma Treatment
por: Klier, John, et al.
Publicado: (2022)

Metalloproteinases and their Inhibitors under the Course of Immunostimulation by CPG-ODN and Specific Antigen Inhalation in Equine Asthma
por: Barton, Ann Kristin, et al.
Publicado: (2019)

Pulmonary Remodeling in Equine Asthma: What Do We Know about Mediators of Inflammation in the Horse?
por: Barton, Ann Kristin, et al.
Publicado: (2016)

A Systematic Approach to Dissection of the Equine Brain–Evaluation of a Species-Adapted Protocol for Beginners and Experts
por: Bitschi, Maya-Lena, et al.
Publicado: (2020)

Procalcitonin as a biomarker in equine chronic pneumopathies
por: Barton, Ann Kristin, et al.
Publicado: (2016)

A comparative survey of veterinarians, equine owners, and equine keepers regarding the knowledge and implementation of legal requirements in Germany for the use and documentation of veterinary medicines in equines intended for slaughter
por: Schneider, Shary Tamara, et al.
Publicado: (2023)

Verification of documentation plausibility in equine passports–drug documentation for geldings in comparison to self-reported veterinarian drug usage for equine castrations in Germany
por: Schneider, Shary Tamara, et al.
Publicado: (2023)

Are pulmonary hemostasis and fibrinolysis out of balance in equine chronic pneumopathies?
por: Barton, Ann Kristin, et al.
Publicado: (2017)

Metabolic syndrome: is equine disease comparable to what we know in humans?
por: Ertelt, Antonia, et al.
Publicado: (2014)

Equine Arteritis Virus (EAV) Outbreak in a Show Stallion Population
por: Otzdorff, Christiane, et al.
Publicado: (2021)

Comparison of Sources and Methods for the Isolation of Equine Adipose Tissue-Derived Stromal/Stem Cells and Preliminary Results on Their Reaction to Incubation with 5-Azacytidine
por: Trachsel, Dagmar S., et al.
Publicado: (2022)

Multilineage Differentiation Potential of Equine Adipose-Derived Stromal/Stem Cells from Different Sources
por: Stage, Hannah J., et al.
Publicado: (2023)

Metalloproteinases and their inhibitors are influenced by inhalative glucocorticoid therapy in combination with environmental dust reduction in equine recurrent airway obstruction
por: Barton, Ann Kristin, et al.
Publicado: (2016)

Nanoparticulate CpG Immunotherapy in RAO‐Affected Horses: Phase I and IIa Study
por: Klier, J., et al.
Publicado: (2015)

Keeping Stallions in Groups—Species-Appropriate or Relevant to Animal Welfare?
por: Gehlen, Heidrun, et al.
Publicado: (2021)

Histopathologic Findings Following Experimental Equine Herpesvirus 1 Infection of Horses
por: Holz, Carine L., et al.
Publicado: (2019)

Comparative Analysis of Intestinal Helminth Infections in Colic and Non-Colic Control Equine Patients
por: Gehlen, Heidrun, et al.
Publicado: (2020)

Immunomodulatory Role of Adipose-Derived Stem Cells on Equine Endometriosis
por: Falomo, Maria Elena, et al.
Publicado: (2015)

Functional properties of equine adipose-derived mesenchymal stromal cells cultured with equine platelet lysate
por: Hagen, Alina, et al.
Publicado: (2022)

MMP-9 Concentration in Peritoneal Fluid Is a Valuable Biomarker Associated with Endotoxemia in Equine Colic
por: Barton, Ann Kristin, et al.
Publicado: (2021)

New Insights into the Management of an EHV-1 (Equine Hospital) Outbreak
por: Vandenberghe, Eveline, et al.
Publicado: (2021)

Molecular Characterization of Equine Staphylococcus aureus Isolates Exhibiting Reduced Oxacillin Susceptibility
por: Scholtzek, Anissa D., et al.
Publicado: (2019)

The gut microbiome of horses: current research on equine enteral microbiota and future perspectives
por: Kauter, Anne, et al.
Publicado: (2019)

Can Endocrine Dysfunction Be Reliably Tested in Aged Horses That Are Experiencing Pain?
por: Gehlen, Heidrun, et al.
Publicado: (2020)

Phenotypic and Immunomodulatory Properties of Equine Cord Blood-Derived Mesenchymal Stromal Cells
por: Tessier, Laurence, et al.
Publicado: (2015)

Adaptogenic and Immunomodulatory Activity of Ashwagandha Root Extract: An Experimental Study in an Equine Model
por: Priyanka, G., et al.
Publicado: (2020)

Photodermatitis and ocular changes in nine horses after ingestion of wild parsnip (pastinaca sativa)
por: Winter, Judith C., et al.
Publicado: (2022)

A Pilot Randomised Clinical Trial Comparing a Short-Term Perioperative Prophylaxis Regimen to a Long-Term Standard Protocol in Equine Colic Surgery
por: Stöckle, Sabita Diana, et al.
Publicado: (2021)

Equine Methicillin-Resistant Sequence Type 398 Staphylococcus aureus (MRSA) Harbor Mobile Genetic Elements Promoting Host Adaptation
por: Walther, Birgit, et al.
Publicado: (2018)

Efficacy of tamoxifen for the treatment of severe equine asthma
por: Mainguy‐Seers, Sophie, et al.
Publicado: (2018)

Equine Asthma: Current Understanding and Future Directions
por: Couetil, Laurent, et al.
Publicado: (2020)

Experimental infection with equine herpesvirus type 1 (EHV-1) induces chorioretinal lesions
por: Hussey, Gisela Soboll, et al.
Publicado: (2013)

Control of moderate-to-severe asthma with randomized ciclesonide doses of 160, 320 and 640 μg/day
por: Pedersen, Søren E, et al.
Publicado: (2017)

Markers for internal neoplasia in the horse
por: Drozdzewska, Karolina, et al.
Publicado: (2022)

Efficacy of inhaled budesonide for the treatment of severe equine asthma
por: Lavoie, J. P., et al.
Publicado: (2018)

Gene Expression Profiles of the Immuno-Transcriptome in Equine Asthma
por: Padoan, Elisa, et al.
Publicado: (2022)

Equid herpesvirus-1 Distribution in Equine Lymphoid and Neural Tissues 70 Days Post Infection
por: Samoilowa, Susanna, et al.
Publicado: (2021)

Characterization and profiling of immunomodulatory genes of equine mesenchymal stromal cells from non-invasive sources
por: De Schauwer, Catharina, et al.
Publicado: (2014)

Pre-conditioning of Equine Bone Marrow-Derived Mesenchymal Stromal Cells Increases Their Immunomodulatory Capacity
por: Caffi, Valeria, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_kulnjfb6qfjiml8m23kf56g67s