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Beyond the Trinity of ATM, ATR, and DNA-PK: Multiple Kinases Shape the DNA Damage Response in Concert With RNA Metabolism

Our genome is constantly exposed to endogenous and exogenous sources of DNA damage resulting in various alterations of the genetic code. DNA double-strand breaks (DSBs) are considered one of the most cytotoxic lesions. Several types of repair pathways act to repair DNA damage and maintain genome sta...

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Detalles Bibliográficos
Autores principales:	Burger, Kaspar, Ketley, Ruth F., Gullerova, Monika
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688092/ https://www.ncbi.nlm.nih.gov/pubmed/31428617 http://dx.doi.org/10.3389/fmolb.2019.00061

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