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Disarming Pseudomonas aeruginosa Virulence by the Inhibitory Action of 1,10-Phenanthroline-5,6-Dione-Based Compounds: Elastase B (LasB) as a Chemotherapeutic Target

Elastase B (lasB) is a multifunctional metalloenzyme secreted by the gram-negative pathogen Pseudomonas aeruginosa, and this enzyme orchestrates several physiopathological events during bacteria-host interplays. LasB is considered to be a potential target for the development of an innovative chemoth...

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Detalles Bibliográficos
Autores principales:	Galdino, Anna Clara M., Viganor, Lívia, de Castro, Alexandre A., da Cunha, Elaine F. F., Mello, Thaís P., Mattos, Larissa M., Pereira, Marcos D., Hunt, Mary C., O’Shaughnessy, Megan, Howe, Orla, Devereux, Michael, McCann, Malachy, Ramalho, Teodorico C., Branquinha, Marta H., Santos, André L. S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688126/ https://www.ncbi.nlm.nih.gov/pubmed/31428062 http://dx.doi.org/10.3389/fmicb.2019.01701

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