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Wee1 Inhibitor AZD1775 Effectively Inhibits the Malignant Phenotypes of Esophageal Squamous Cell Carcinoma In Vitro and In Vivo

Esophageal squamous cell carcinoma (ESCC) is a common malignant diagnosed cancer with increasing incidence rate and few treatment options. As a specific small-molecule inhibitor of the Wee1 tyrosine kinase, AZD1775 has previously shown potent antitumor effect on multiple types of cancer in various p...

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Detalles Bibliográficos
Autores principales:	Bi, Shuning, Wei, Qiuren, Zhao, Zhijun, Chen, Liang, Wang, Chaojie, Xie, Songqiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688135/ https://www.ncbi.nlm.nih.gov/pubmed/31427973 http://dx.doi.org/10.3389/fphar.2019.00864

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