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Tuberculosis osteomyelitis of the tibia mimicking Brodie abscess: A case report and review of the literature

BACKGROUND: Tuberculosis osteomyelitis is rarely seen in the diaphyseal bones. It may be confused with Brodie’s abscess due to similar clinical, radiological and laboratory findings. Late diagnosis of the disease causes bone destruction. Tuberculosis osteomyelitis of the bone is a rare condition cau...

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Autores principales: Sari, Abdülkadir, Dinçel, Yaşar Mahsut, Erdogdu, Ibrahim Halil, Sayıner, Hakan Sezgin, Agir, Ismail, Çetin, Mehmet Ümit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688143/
https://www.ncbi.nlm.nih.gov/pubmed/31448121
http://dx.doi.org/10.1177/2050313X19869455
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author Sari, Abdülkadir
Dinçel, Yaşar Mahsut
Erdogdu, Ibrahim Halil
Sayıner, Hakan Sezgin
Agir, Ismail
Çetin, Mehmet Ümit
author_facet Sari, Abdülkadir
Dinçel, Yaşar Mahsut
Erdogdu, Ibrahim Halil
Sayıner, Hakan Sezgin
Agir, Ismail
Çetin, Mehmet Ümit
author_sort Sari, Abdülkadir
collection PubMed
description BACKGROUND: Tuberculosis osteomyelitis is rarely seen in the diaphyseal bones. It may be confused with Brodie’s abscess due to similar clinical, radiological and laboratory findings. Late diagnosis of the disease causes bone destruction. Tuberculosis osteomyelitis of the bone is a rare condition caused by the Mycobacterium tuberculosis. Its incidence has increased in Western countries in recent years due to HIV infection, increasing elderly population and emerging resistant strains. The slow progress of tuberculous osteomyelitis, due to lack of significant elevations in the laboratory values and changes in the radiographic appearance, often leads to confusion with the subtypes of subacute osteomyelitis, defined as Brodie’s abscess. These two low-virulence clinical cases often lead to delays in diagnosis and progressive bone destruction. CASE PRESENTATION: We report a 65-year-old male patient who presented to our clinic with pain, swelling and sensitivity in the left leg. Diagnosed with infection in the tibia, the patient had undergone antibiotherapy. However, the patient’s symptoms were not resolved and we performed bone curettage and cementation. M. tuberculosis-specific DNA was detected by real-time polymerase chain reaction and the M. tuberculosis complex was produced from the perioperative samples. CONCLUSION: In conclusion, histopathological examination and polymerase chain reaction are essential before surgery of subacute and chronic osteomyelitis with atypical clinical, laboratory and radiological findings for early diagnosis and accurate treatment.
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spelling pubmed-66881432019-08-23 Tuberculosis osteomyelitis of the tibia mimicking Brodie abscess: A case report and review of the literature Sari, Abdülkadir Dinçel, Yaşar Mahsut Erdogdu, Ibrahim Halil Sayıner, Hakan Sezgin Agir, Ismail Çetin, Mehmet Ümit SAGE Open Med Case Rep Case Report BACKGROUND: Tuberculosis osteomyelitis is rarely seen in the diaphyseal bones. It may be confused with Brodie’s abscess due to similar clinical, radiological and laboratory findings. Late diagnosis of the disease causes bone destruction. Tuberculosis osteomyelitis of the bone is a rare condition caused by the Mycobacterium tuberculosis. Its incidence has increased in Western countries in recent years due to HIV infection, increasing elderly population and emerging resistant strains. The slow progress of tuberculous osteomyelitis, due to lack of significant elevations in the laboratory values and changes in the radiographic appearance, often leads to confusion with the subtypes of subacute osteomyelitis, defined as Brodie’s abscess. These two low-virulence clinical cases often lead to delays in diagnosis and progressive bone destruction. CASE PRESENTATION: We report a 65-year-old male patient who presented to our clinic with pain, swelling and sensitivity in the left leg. Diagnosed with infection in the tibia, the patient had undergone antibiotherapy. However, the patient’s symptoms were not resolved and we performed bone curettage and cementation. M. tuberculosis-specific DNA was detected by real-time polymerase chain reaction and the M. tuberculosis complex was produced from the perioperative samples. CONCLUSION: In conclusion, histopathological examination and polymerase chain reaction are essential before surgery of subacute and chronic osteomyelitis with atypical clinical, laboratory and radiological findings for early diagnosis and accurate treatment. SAGE Publications 2019-08-08 /pmc/articles/PMC6688143/ /pubmed/31448121 http://dx.doi.org/10.1177/2050313X19869455 Text en © The Author(s) 2019 http://www.creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Sari, Abdülkadir
Dinçel, Yaşar Mahsut
Erdogdu, Ibrahim Halil
Sayıner, Hakan Sezgin
Agir, Ismail
Çetin, Mehmet Ümit
Tuberculosis osteomyelitis of the tibia mimicking Brodie abscess: A case report and review of the literature
title Tuberculosis osteomyelitis of the tibia mimicking Brodie abscess: A case report and review of the literature
title_full Tuberculosis osteomyelitis of the tibia mimicking Brodie abscess: A case report and review of the literature
title_fullStr Tuberculosis osteomyelitis of the tibia mimicking Brodie abscess: A case report and review of the literature
title_full_unstemmed Tuberculosis osteomyelitis of the tibia mimicking Brodie abscess: A case report and review of the literature
title_short Tuberculosis osteomyelitis of the tibia mimicking Brodie abscess: A case report and review of the literature
title_sort tuberculosis osteomyelitis of the tibia mimicking brodie abscess: a case report and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688143/
https://www.ncbi.nlm.nih.gov/pubmed/31448121
http://dx.doi.org/10.1177/2050313X19869455
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