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ZFP57 regulation of transposable elements and gene expression within and beyond imprinted domains

BACKGROUND: KRAB zinc finger proteins (KZFPs) represent one of the largest families of DNA-binding proteins in vertebrate genomes and appear to have evolved to silence transposable elements (TEs) including endogenous retroviruses through sequence-specific targeting of repressive chromatin states. ZF...

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Detalles Bibliográficos
Autores principales: Shi, Hui, Strogantsev, Ruslan, Takahashi, Nozomi, Kazachenka, Anastasiya, Lorincz, Matthew C., Hemberger, Myriam, Ferguson-Smith, Anne C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688207/
https://www.ncbi.nlm.nih.gov/pubmed/31399135
http://dx.doi.org/10.1186/s13072-019-0295-4