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ZFP57 regulation of transposable elements and gene expression within and beyond imprinted domains
BACKGROUND: KRAB zinc finger proteins (KZFPs) represent one of the largest families of DNA-binding proteins in vertebrate genomes and appear to have evolved to silence transposable elements (TEs) including endogenous retroviruses through sequence-specific targeting of repressive chromatin states. ZF...
Autores principales: | Shi, Hui, Strogantsev, Ruslan, Takahashi, Nozomi, Kazachenka, Anastasiya, Lorincz, Matthew C., Hemberger, Myriam, Ferguson-Smith, Anne C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688207/ https://www.ncbi.nlm.nih.gov/pubmed/31399135 http://dx.doi.org/10.1186/s13072-019-0295-4 |
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