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Water extract of Cnidii Rhizoma suppresses RANKL-induced osteoclastogenesis in RAW 264.7 cell by inhibiting NFATc1/c-Fos signaling and prevents ovariectomized bone loss in SD-rat

BACKGROUND: Cnidii Rhizoma is the dried root stem of Cnidium officinale Makino. Cnidii Rhizoma (CR) has been used to treat menstrual irregularity, menstrual pain, and menopause in Korea. However, the effects and mechanisms of CR on RANKL-induced osteoclastogenesis pathway remain to be elucidated. In...

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Detalles Bibliográficos
Autores principales:	Lee, Ka-Yeon, Kim, Jae-Hyun, Kim, Eun-Young, Yeom, Mijung, Jung, Hyuk-Sang, Sohn, Youngjoo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688344/ https://www.ncbi.nlm.nih.gov/pubmed/31399090 http://dx.doi.org/10.1186/s12906-019-2611-8

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