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The Internet-Based Cognitive Assessment Tool: System Design and Feasibility Study

BACKGROUND: Persistent cognitive impairment is prevalent in unipolar and bipolar disorders and is associated with decreased quality of life and psychosocial dysfunction. The screen for cognitive impairment in psychiatry (SCIP) test is a validated paper-and-pencil instrument for the assessment of cog...

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Autores principales: Hafiz, Pegah, Miskowiak, Kamilla Woznica, Kessing, Lars Vedel, Elleby Jespersen, Andreas, Obenhausen, Kia, Gulyas, Lorant, Zukowska, Katarzyna, Bardram, Jakob Eyvind
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JMIR Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688443/
https://www.ncbi.nlm.nih.gov/pubmed/31350840
http://dx.doi.org/10.2196/13898
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author Hafiz, Pegah
Miskowiak, Kamilla Woznica
Kessing, Lars Vedel
Elleby Jespersen, Andreas
Obenhausen, Kia
Gulyas, Lorant
Zukowska, Katarzyna
Bardram, Jakob Eyvind
author_facet Hafiz, Pegah
Miskowiak, Kamilla Woznica
Kessing, Lars Vedel
Elleby Jespersen, Andreas
Obenhausen, Kia
Gulyas, Lorant
Zukowska, Katarzyna
Bardram, Jakob Eyvind
author_sort Hafiz, Pegah
collection PubMed
description BACKGROUND: Persistent cognitive impairment is prevalent in unipolar and bipolar disorders and is associated with decreased quality of life and psychosocial dysfunction. The screen for cognitive impairment in psychiatry (SCIP) test is a validated paper-and-pencil instrument for the assessment of cognition in affective disorders. However, there is no digital cognitive screening tool for the brief and accurate assessment of cognitive impairments in this patient group. OBJECTIVE: In this paper, we present the design process and feasibility study of the internet-based cognitive assessment tool (ICAT) that is designed based on the cognitive tasks of the SCIP. The aims of this feasibility study were to perform the following tasks among healthy individuals: (1) evaluate the usability of the ICAT, (2) investigate the feasibility of the ICAT as a patient-administered cognitive assessment tool, and (3) examine the performance of automatic speech recognition (ASR) for the assessment of verbal recall. METHODS: The ICAT was developed in a user-centered design process. The cognitive measures of the ICAT were immediate and delayed recall, working memory, and psychomotor speed. Usability and feasibility studies were conducted separately with 2 groups of healthy individuals (N=21 and N=19, respectively). ICAT tests were available in the English and Danish languages. The participants were asked to fill in the post study system usability questionnaire (PSSUQ) upon completing the ICAT test. Verbal recall in the ICAT was assessed using ASR, and the performance evaluation criterion was word error rate (WER). A Pearson 2-tailed correlation analysis significant at the .05 level was applied to investigate the association between the SCIP and ICAT scores. RESULTS: The overall psychometric factors of PSSUQ for both studies gave scores above 4 (out of 5). The analysis of the feasibility study revealed a moderate to strong correlation between the total scores of the SCIP and ICAT (r=0.63; P=.009). There were also moderate to strong correlations between the SCIP and ICAT subtests for immediate verbal recall (r=0.67; P=.002) and psychomotor speed (r=0.71; P=.001). The associations between the respective subtests for working memory, executive function, and delayed recall, however, were not statistically significant. The corresponding WER for English and Danish responses were 17.8% and 6.3%, respectively. CONCLUSIONS: The ICAT is the first digital screening instrument modified from the SCIP using Web-based technology and ASR. There was good accuracy of the ASR for verbal memory assessment. The moderate correlation between the ICAT and SCIP scores suggests that the ICAT is a valid tool for assessing cognition, although this should be confirmed in a larger study with greater statistical power. Taken together, the ICAT seems to be a valid Web-based cognitive assessment tool that, after some minor modifications and further validation, may be used to screen for cognitive impairment in clinical settings.
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spelling pubmed-66884432019-08-20 The Internet-Based Cognitive Assessment Tool: System Design and Feasibility Study Hafiz, Pegah Miskowiak, Kamilla Woznica Kessing, Lars Vedel Elleby Jespersen, Andreas Obenhausen, Kia Gulyas, Lorant Zukowska, Katarzyna Bardram, Jakob Eyvind JMIR Form Res Original Paper BACKGROUND: Persistent cognitive impairment is prevalent in unipolar and bipolar disorders and is associated with decreased quality of life and psychosocial dysfunction. The screen for cognitive impairment in psychiatry (SCIP) test is a validated paper-and-pencil instrument for the assessment of cognition in affective disorders. However, there is no digital cognitive screening tool for the brief and accurate assessment of cognitive impairments in this patient group. OBJECTIVE: In this paper, we present the design process and feasibility study of the internet-based cognitive assessment tool (ICAT) that is designed based on the cognitive tasks of the SCIP. The aims of this feasibility study were to perform the following tasks among healthy individuals: (1) evaluate the usability of the ICAT, (2) investigate the feasibility of the ICAT as a patient-administered cognitive assessment tool, and (3) examine the performance of automatic speech recognition (ASR) for the assessment of verbal recall. METHODS: The ICAT was developed in a user-centered design process. The cognitive measures of the ICAT were immediate and delayed recall, working memory, and psychomotor speed. Usability and feasibility studies were conducted separately with 2 groups of healthy individuals (N=21 and N=19, respectively). ICAT tests were available in the English and Danish languages. The participants were asked to fill in the post study system usability questionnaire (PSSUQ) upon completing the ICAT test. Verbal recall in the ICAT was assessed using ASR, and the performance evaluation criterion was word error rate (WER). A Pearson 2-tailed correlation analysis significant at the .05 level was applied to investigate the association between the SCIP and ICAT scores. RESULTS: The overall psychometric factors of PSSUQ for both studies gave scores above 4 (out of 5). The analysis of the feasibility study revealed a moderate to strong correlation between the total scores of the SCIP and ICAT (r=0.63; P=.009). There were also moderate to strong correlations between the SCIP and ICAT subtests for immediate verbal recall (r=0.67; P=.002) and psychomotor speed (r=0.71; P=.001). The associations between the respective subtests for working memory, executive function, and delayed recall, however, were not statistically significant. The corresponding WER for English and Danish responses were 17.8% and 6.3%, respectively. CONCLUSIONS: The ICAT is the first digital screening instrument modified from the SCIP using Web-based technology and ASR. There was good accuracy of the ASR for verbal memory assessment. The moderate correlation between the ICAT and SCIP scores suggests that the ICAT is a valid tool for assessing cognition, although this should be confirmed in a larger study with greater statistical power. Taken together, the ICAT seems to be a valid Web-based cognitive assessment tool that, after some minor modifications and further validation, may be used to screen for cognitive impairment in clinical settings. JMIR Publications 2019-07-26 /pmc/articles/PMC6688443/ /pubmed/31350840 http://dx.doi.org/10.2196/13898 Text en ©Pegah Hafiz, Kamilla Woznica Miskowiak, Lars Vedel Kessing, Andreas Elleby Jespersen, Kia Obenhausen, Lorant Gulyas, Katarzyna Zukowska, Jakob Eyvind Bardram. Originally published in JMIR Formative Research (http://formative.jmir.org), 26.07.2019. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Formative Research, is properly cited. The complete bibliographic information, a link to the original publication on http://formative.jmir.org, as well as this copyright and license information must be included.
spellingShingle Original Paper
Hafiz, Pegah
Miskowiak, Kamilla Woznica
Kessing, Lars Vedel
Elleby Jespersen, Andreas
Obenhausen, Kia
Gulyas, Lorant
Zukowska, Katarzyna
Bardram, Jakob Eyvind
The Internet-Based Cognitive Assessment Tool: System Design and Feasibility Study
title The Internet-Based Cognitive Assessment Tool: System Design and Feasibility Study
title_full The Internet-Based Cognitive Assessment Tool: System Design and Feasibility Study
title_fullStr The Internet-Based Cognitive Assessment Tool: System Design and Feasibility Study
title_full_unstemmed The Internet-Based Cognitive Assessment Tool: System Design and Feasibility Study
title_short The Internet-Based Cognitive Assessment Tool: System Design and Feasibility Study
title_sort internet-based cognitive assessment tool: system design and feasibility study
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688443/
https://www.ncbi.nlm.nih.gov/pubmed/31350840
http://dx.doi.org/10.2196/13898
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