Cargando…

Fibroblast-Like Synoviocytes Glucose Metabolism as a Therapeutic Target in Rheumatoid Arthritis

Metabolomic studies show that rheumatoid arthritis (RA) is associated with metabolic disruption that may be therapeutically targetable. Among them, glucose metabolism and glycolytic intermediaries seem to have an important role in fibroblast-like synoviocytes (FLS) phenotype and might contribute to...

Descripción completa

Detalles Bibliográficos
Autores principales:	de Oliveira, Patricia Gnieslaw, Farinon, Mirian, Sanchez-Lopez, Elsa, Miyamoto, Shigeki, Guma, Monica
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688519/ https://www.ncbi.nlm.nih.gov/pubmed/31428089 http://dx.doi.org/10.3389/fimmu.2019.01743

Ejemplares similares

Role of mitochondria-bound HK2 in rheumatoid arthritis fibroblast-like synoviocytes
por: Torres, Alyssa, et al.
Publicado: (2023)

Solute carrier nutrient transporters in rheumatoid arthritis fibroblast-like synoviocytes
por: Torres, Alyssa, et al.
Publicado: (2022)

Fibroblast-like synoviocyte metabolism in the pathogenesis of rheumatoid arthritis
por: Bustamante, Marta F., et al.
Publicado: (2017)

Kirenol Inhibits the Function and Inflammation of Fibroblast-like Synoviocytes in Rheumatoid Arthritis in vitro and in vivo
por: Wu, Jing, et al.
Publicado: (2019)

Role and mechanism of fibroblast-activated protein-α expression on the surface of fibroblast-like synoviocytes in rheumatoid arthritis
por: Wang, Zihan, et al.
Publicado: (2023)

Editorial: Immunomodulatory Functions of Fibroblast-like Synoviocytes in Joint Inflammation and Destruction during Rheumatoid Arthritis
por: Xu, Hanshi, et al.
Publicado: (2020)

C-Reactive Protein Promotes the Activation of Fibroblast-Like Synoviocytes From Patients With Rheumatoid Arthritis
por: Fang, Zhengyu, et al.
Publicado: (2020)

SFRP1 Negatively Modulates Pyroptosis of Fibroblast‐Like Synoviocytes in Rheumatoid Arthritis: A Review
por: Jiang, Ping, et al.
Publicado: (2022)

Photobiomodulation ameliorates inflammatory parameters in fibroblast-like synoviocytes and experimental animal models of rheumatoid arthritis
por: Ryu, Ji Hyeon, et al.
Publicado: (2023)

Smoothened Regulates Migration of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis via Activation of Rho GTPase Signaling
por: Peng, Wei-xiang, et al.
Publicado: (2017)

SFRP5 Enhances Wnt5a Induced-Inflammation in Rheumatoid Arthritis Fibroblast-Like Synoviocytes
por: Mahmoud, Dorra Elhaj, et al.
Publicado: (2021)

The synovial fluid fibroblast-like synoviocyte: A long-neglected piece in the puzzle of rheumatoid arthritis pathogenesis
por: Mahmoud, Dorra Elhaj, et al.
Publicado: (2022)

The Rheumatoid Arthritis Risk Gene AIRE Is Induced by Cytokines in Fibroblast-Like Synoviocytes and Augments the Pro-inflammatory Response
por: Bergström, Beatrice, et al.
Publicado: (2019)

Two Main Cellular Components in Rheumatoid Arthritis: Communication Between T Cells and Fibroblast-Like Synoviocytes in the Joint Synovium
por: Tu, Jiajie, et al.
Publicado: (2022)

YAP/TAZ: Key Players for Rheumatoid Arthritis Severity by Driving Fibroblast Like Synoviocytes Phenotype and Fibro-Inflammatory Response
por: Caire, Robin, et al.
Publicado: (2021)

Chemerin activates fibroblast-like synoviocytes in patients with rheumatoid arthritis
por: Kaneko, Kayoko, et al.
Publicado: (2011)

Comprehensive epigenetic landscape of rheumatoid arthritis fibroblast-like synoviocytes
por: Ai, Rizi, et al.
Publicado: (2018)

Ontology and Function of Fibroblast-Like and Macrophage-Like Synoviocytes: How Do They Talk to Each Other and Can They Be Targeted for Rheumatoid Arthritis Therapy?
por: Tu, Jiajie, et al.
Publicado: (2018)

Metabolomic Elucidation of the Effects of Curcumin on Fibroblast-Like Synoviocytes in Rheumatoid Arthritis
por: Ahn, Joong Kyong, et al.
Publicado: (2015)

Oridonin suppresses autophagy and survival in rheumatoid arthritis fibroblast-like synoviocytes
por: He, Shou-Di, et al.
Publicado: (2020)

Sonic Hedgehog Signaling Pathway Mediates Proliferation and Migration of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis via MAPK/ERK Signaling Pathway
por: Liu, Fang, et al.
Publicado: (2018)

Long Non-Coding RNA GAPLINC Promotes Tumor-Like Biologic Behaviors of Fibroblast-Like Synoviocytes as MicroRNA Sponging in Rheumatoid Arthritis Patients
por: Mo, Bi Yao, et al.
Publicado: (2018)

Glucose-6-phosphate isomerase promotes the proliferation and inhibits the apoptosis in fibroblast-like synoviocytes in rheumatoid arthritis
por: Zong, Ming, et al.
Publicado: (2015)

Kruppel-Like Factor 4 Positively Regulates Autoimmune Arthritis in Mouse Models and Rheumatoid Arthritis in Patients via Modulating Cell Survival and Inflammation Factors of Fibroblast-Like Synoviocyte
por: Choi, Seungjin, et al.
Publicado: (2018)

TRAIL-induced rheumatoid arthritis fibroblast-like synoviocyte proliferation is inhibited by OPG
por: Morel, J, et al.
Publicado: (2004)

15-Hydroxyprostaglandin dehydrogenase is upregulated by hydroxychloroquine in rheumatoid arthritis fibroblast-like synoviocytes
por: KIM, HAK-JAE, et al.
Publicado: (2015)

Thioredoxin 1 is associated with the proliferation and apoptosis of rheumatoid arthritis fibroblast-like synoviocytes
por: Lu, Tianbao, et al.
Publicado: (2017)

RHAMM induces progression of rheumatoid arthritis by enhancing the functions of fibroblast-like synoviocytes
por: Wu, Jing, et al.
Publicado: (2018)

Expression of AIM2 in Rheumatoid Arthritis and Its Role on Fibroblast-Like Synoviocytes
por: Chen, Yong, et al.
Publicado: (2020)

NF-κB signaling in rheumatoid arthritis with focus on fibroblast-like synoviocytes
por: Nejatbakhsh Samimi, Leila, et al.
Publicado: (2020)

Quercetin suppresses inflammatory cytokine production in rheumatoid arthritis fibroblast-like synoviocytes
por: Sun, Hai-Tao, et al.
Publicado: (2021)

Tofacitinib Decreases Autophagy of Fibroblast-Like Synoviocytes From Rheumatoid Arthritis Patients
por: Vomero, M., et al.
Publicado: (2022)

Transformation of fibroblast‐like synoviocytes in rheumatoid arthritis; from a friend to foe
por: Mousavi, Mohammad Javad, et al.
Publicado: (2021)

PTEN Methylation Promotes Inflammation and Activation of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis
por: Li, Xiao-Feng, et al.
Publicado: (2021)

LncRNA NEAT1 Targets Fibroblast-Like Synoviocytes in Rheumatoid Arthritis via the miR-410-3p/YY1 Axis
por: Wang, Yuejiao, et al.
Publicado: (2020)

Circ_0088194 Promotes the Invasion and Migration of Rheumatoid Arthritis Fibroblast-Like Synoviocytes via the miR-766-3p/MMP2 Axis
por: Cai, Yujie, et al.
Publicado: (2021)

Regulation of Immune Responses and Chronic Inflammation by Fibroblast-Like Synoviocytes
por: Yoshitomi, Hiroyuki
Publicado: (2019)

Can Metabolic Pathways Be Therapeutic Targets in Rheumatoid Arthritis?
por: Sanchez-Lopez, Elsa, et al.
Publicado: (2019)

Effects of inflammatory cytokine IL-27 on the activation of fibroblast-like synoviocytes in rheumatoid arthritis
por: Wong, Chun K, et al.
Publicado: (2010)

Innate immunity triggers IL-32 expression by fibroblast-like synoviocytes in rheumatoid arthritis
por: Alsaleh, Ghada, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_oqlli0jqu50jtrqed3ekm03dcn