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Effects of Pre–Cardiopulmonary Bypass Administration of Dexmedetomidine on Cardiac Injuries and the Inflammatory Response in Valve Replacement Surgery With a Sevoflurane Postconditioning Protocol: A Pilot Study

BACKGROUND: Preventing myocardial ischemia–reperfusion injury in on-pump cardiac surgeries remains an enormous challenge. Sevoflurane postconditioning has been effective at overcoming this challenge by modulating inflammatory mediators and ameliorating antioxidative stress. Dexmedetomidine (DEX) is...

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Detalles Bibliográficos
Autores principales:	Zhou, Hongmei, Zhou, Dongna, Lu, Jian, Wu, Cheng, Zhu, Zhipeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Journal of Cardiovascular Pharmacology 2019
Materias:	Clinical Trials
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688713/ https://www.ncbi.nlm.nih.gov/pubmed/31356535 http://dx.doi.org/10.1097/FJC.0000000000000698

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