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Phase 3 DREAM-HF Trial of Mesenchymal Precursor Cells in Chronic Heart Failure: A Review of Biological Plausibility and Implementation of Flexible Clinical Trial Design

Advanced heart failure (HF) is a progressive disease characterized by recurrent hospitalizations and high risk of mortality. Indeed, outcomes in late stages of HF approximate those seen in patients with various aggressive malignancies. Clinical trials assessing beneficial outcomes of new treatments...

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Detalles Bibliográficos
Autores principales:	Borow, Kenneth M., Yaroshinsky, Alex, Greenberg, Barry, Perin, Emerson C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2019
Materias:	Special Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688717/ https://www.ncbi.nlm.nih.gov/pubmed/31318648 http://dx.doi.org/10.1161/CIRCRESAHA.119.314951

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