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Akt1-mediated CPR cooling protection targets regulators of metabolism, inflammation and contractile function in mouse cardiac arrest

Therapeutic hypothermia initiated during cardiopulmonary resuscitation (CPR) in pre-clinical studies appears to be highly protective against sudden cardiac arrest injury. Given the challenges to implementing CPR cooling clinically, insights into its critical mechanisms of protection could guide deve...

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Detalles Bibliográficos
Autores principales:	Li, Jing, Zhu, Xiangdong, Wang, Huashan, Lee, Chunpei, Chen, Sy-Jou, Qian, Yuanyu, Han, Mei, Bunney, Ryan, Beiser, David G., Vanden Hoek, Terry L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688812/ https://www.ncbi.nlm.nih.gov/pubmed/31398213 http://dx.doi.org/10.1371/journal.pone.0220604

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