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Impact of Itga2-Gp6-double collagen receptor deficient mice for bone marrow megakaryocytes and platelets
The two main collagen receptors on platelets, GPVI and integrin α2β1, play an important role for the recognition of exposed collagen at sites of vessel injury, which leads to platelet activation and subsequently stable thrombus formation. Both receptors are already expressed on megakaryocytes, the p...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688823/ https://www.ncbi.nlm.nih.gov/pubmed/31398205 http://dx.doi.org/10.1371/journal.pone.0216839 |