The impact of chemo- and radiotherapy treatments on selfish de novo FGFR2 mutations in sperm of cancer survivors

STUDY QUESTION: What effect does cancer treatment have on levels of spontaneous selfish fibroblast growth factor receptor 2 (FGFR2) point mutations in human sperm? SUMMARY ANSWER: Chemotherapy and radiotherapy do not increase levels of spontaneous FGFR2 mutations in sperm but, unexpectedly, highly-s...

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Detalles Bibliográficos
Autores principales: Maher, Geoffrey J, Bernkopf, Marie, Koelling, Nils, Wilkie, Andrew O M, Meistrich, Marvin L, Goriely, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688873/
https://www.ncbi.nlm.nih.gov/pubmed/31348830
http://dx.doi.org/10.1093/humrep/dez090

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