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HSP90 inhibitors stimulate DNAJB4 protein expression through a mechanism involving N(6)-methyladenosine

Small-molecule inhibitors for the 90-kDa heat shock protein (HSP90) have been extensively exploited in preclinical studies for the therapeutic interventions of human diseases accompanied with proteotoxic stress. By using an unbiased quantitative proteomic method, we uncover that treatment with three...

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Detalles Bibliográficos
Autores principales: Miao, Weili, Li, Lin, Zhao, Yonghui, Dai, Xiaoxia, Chen, Xuemei, Wang, Yinsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688989/
https://www.ncbi.nlm.nih.gov/pubmed/31399576
http://dx.doi.org/10.1038/s41467-019-11552-8

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