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Efficient derivation of knock-out and knock-in rats using embryos obtained by in vitro fertilization
Rats are effective model animals and have contributed to the development of human medicine and basic research. However, the application of reproductive engineering techniques to rats is not as advanced compared with mice, and genome editing in rats has not been achieved using embryos obtained by in...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689013/ https://www.ncbi.nlm.nih.gov/pubmed/31399630 http://dx.doi.org/10.1038/s41598-019-47964-1 |