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Variable impact of the hemagglutinin polybasic cleavage site on virulence and pathogenesis of avian influenza H7N7 virus in chickens, turkeys and ducks

Avian influenza viruses (AIV) are classified into 16 hemagglutinin (HA; H1-H16) and 9 neuraminidase (NA; N1-N9) subtypes. All AIV are low pathogenic (LP) in birds, but subtypes H5 and H7 AIV can evolve into highly pathogenic (HP) forms. In the last two decades evolution of HPAIV H7 from LPAIV has be...

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Detalles Bibliográficos
Autores principales:	Scheibner, David, Ulrich, Reiner, Fatola, Olanrewaju I., Graaf, Annika, Gischke, Marcel, Salaheldin, Ahmed H., Harder, Timm C., Veits, Jutta, Mettenleiter, Thomas C., Abdelwhab, Elsayed M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689016/ https://www.ncbi.nlm.nih.gov/pubmed/31399610 http://dx.doi.org/10.1038/s41598-019-47938-3

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