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Pirfenidone in Heart Failure with Preserved Ejection Fraction—Rationale and Design of the PIROUETTE Trial

BACKGROUND: The PIROUETTE (PIRfenidOne in patients with heart failUre and preserved lEfT venTricular Ejection fraction) trial is designed to evaluate the efficacy and safety of the anti-fibrotic pirfenidone in patients with chronic heart failure and preserved ejection fraction (HFpEF) and myocardial...

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Detalles Bibliográficos
Autores principales: Lewis, Gavin A., Schelbert, Erik B., Naish, Josephine H., Bedson, Emma, Dodd, Susanna, Eccleson, Helen, Clayton, Dannii, Jimenez, Beatriz Duran, McDonagh, Theresa, Williams, Simon G., Cooper, Anne, Cunnington, Colin, Ahmed, Fozia Zahir, Viswesvaraiah, Rajavarma, Russell, Stuart, Neubauer, Stefan, Williamson, Paula R., Miller, Christopher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689029/
https://www.ncbi.nlm.nih.gov/pubmed/31069575
http://dx.doi.org/10.1007/s10557-019-06876-y