Cargando…
The Hippo effector TAZ promotes cancer stemness by transcriptional activation of SOX2 in head neck squamous cell carcinoma
The Hippo-TAZ signaling has emerged as a fundamental regulator underlying cancer stem cells (CSCs) stemness which intricately associates with local recurrence and metastatic spreading in head neck squamous cell carcinoma (HNSCC). However, the precise downstream targets of TAZ responsible for HNSCC C...
Autores principales: | Li, Jin, Li, Zhongwu, Wu, Yaping, Wang, Yanling, Wang, Dongmiao, Zhang, Wei, Yuan, Hua, Ye, Jinhai, Song, Xiaomeng, Yang, Jianrong, Jiang, Hongbing, Cheng, Jie |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689034/ https://www.ncbi.nlm.nih.gov/pubmed/31399556 http://dx.doi.org/10.1038/s41419-019-1838-0 |
Ejemplares similares
-
Therapeutic Targeting of BRD4 in Head Neck Squamous Cell Carcinoma
por: Wu, Yaping, et al.
Publicado: (2019) -
Pharmacological activation of TAZ enhances osteogenic differentiation and bone formation of adipose-derived stem cells
por: Zhu, Yumin, et al.
Publicado: (2018) -
SUZ12 is a novel putative oncogene promoting tumorigenesis in head and neck squamous cell carcinoma
por: Wu, Yaping, et al.
Publicado: (2018) -
The effector of Hippo signaling, Taz, is required for formation of the micropyle and fertilization in zebrafish
por: Yi, Xiaogui, et al.
Publicado: (2019) -
TEAD4 overexpression promotes epithelial-mesenchymal transition and associates with aggressiveness and adverse prognosis in head neck squamous cell carcinoma
por: Zhang, Wei, et al.
Publicado: (2018)