A conserved RNA structural motif for organizing topology within picornaviral internal ribosome entry sites

Picornaviral IRES elements are essential for initiating the cap-independent viral translation. However, three-dimensional structures of these elements remain elusive. Here, we report a 2.84-Å resolution crystal structure of hepatitis A virus IRES domain V (dV) in complex with a synthetic antibody fr...

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Detalles Bibliográficos
Autores principales: Koirala, Deepak, Shao, Yaming, Koldobskaya, Yelena, Fuller, James R., Watkins, Andrew M., Shelke, Sandip A., Pilipenko, Evgeny V., Das, Rhiju, Rice, Phoebe A., Piccirilli, Joseph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689051/
https://www.ncbi.nlm.nih.gov/pubmed/31399592
http://dx.doi.org/10.1038/s41467-019-11585-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689051/
https://www.ncbi.nlm.nih.gov/pubmed/31399592
http://dx.doi.org/10.1038/s41467-019-11585-z

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