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Association between the c.415C > T, c.52G > A, and 36_37insGGAGTC polymorphisms of NUDT 15 and thiopurine-induced leukopenia, thiopurine intolerance, and severe hair loss: an updated meta-analysis

PURPOSE: As a common immunosuppressive and anticancer drug, thiopurine has achieved remarkable clinical success. However, higher inter-individual dose variability and unpredictable toxicity still challenge its use in clinical practices. Some studies indicate that NUDT 15 polymorphisms are associated...

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Detalles Bibliográficos
Autores principales:	Wang, Ruili, Liu, Baogang, Li, Jiapeng, Xu, Jiamin, Wang, Xiaoling, Zhao, Zhigang, Zhao, Libo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689127/ https://www.ncbi.nlm.nih.gov/pubmed/31496650 http://dx.doi.org/10.2147/DDDT.S210512

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