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Analysis of Dexmedetomidine on the Quality of Awakening During Neurosurgery

Dexmedetomidine has a dose-dependent sedative and analgesic effect. To further evaluate the wake-up quality of dexmedetomidine in patients undergoing neurosurgery, a meta-analysis of dexmedetomidine in a randomized controlled trial of general anesthesia was performed. Firstly, an experimental algori...

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Detalles Bibliográficos
Autores principales: Cao, Jing, Li, Hui, Song, Shengwen, Zhou, Xuyan, Shen, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689226/
https://www.ncbi.nlm.nih.gov/pubmed/31410296
http://dx.doi.org/10.1515/tnsci-2019-0026
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author Cao, Jing
Li, Hui
Song, Shengwen
Zhou, Xuyan
Shen, Xu
author_facet Cao, Jing
Li, Hui
Song, Shengwen
Zhou, Xuyan
Shen, Xu
author_sort Cao, Jing
collection PubMed
description Dexmedetomidine has a dose-dependent sedative and analgesic effect. To further evaluate the wake-up quality of dexmedetomidine in patients undergoing neurosurgery, a meta-analysis of dexmedetomidine in a randomized controlled trial of general anesthesia was performed. Firstly, an experimental algorithm was proposed, and then the data fusion algorithm was used to conduct randomized controlled trials. The clinical efficacy and safety of dexmedetomidine in the acupuncture of neurosurgical patients were evaluated one by one for quality evaluation and data extraction. The effect of different input variables on the depth of anesthesia was studied by using a multi-data fusion approach. The results show that the data fusion algorithm proposed can effectively connect redundant information and complementary information in multiple data, and estimate the real parameters of the measured object. In addition, data fusion brings great convenience to the design of control algorithms and controllers, and provides an effective basis for system simplification. Experiments have shown that dexmedetomidine is effective and safe in the operation of neurosurgical motor function, and the management of the recovery period is safe and effective. Based on the research, it can provide some reference for the awakening of patients undergoing neurosurgery, and promote the progress and development of medicine.
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spelling pubmed-66892262019-08-13 Analysis of Dexmedetomidine on the Quality of Awakening During Neurosurgery Cao, Jing Li, Hui Song, Shengwen Zhou, Xuyan Shen, Xu Transl Neurosci Special Issue: Adult Neurogenesis and Neurological Disorders Dexmedetomidine has a dose-dependent sedative and analgesic effect. To further evaluate the wake-up quality of dexmedetomidine in patients undergoing neurosurgery, a meta-analysis of dexmedetomidine in a randomized controlled trial of general anesthesia was performed. Firstly, an experimental algorithm was proposed, and then the data fusion algorithm was used to conduct randomized controlled trials. The clinical efficacy and safety of dexmedetomidine in the acupuncture of neurosurgical patients were evaluated one by one for quality evaluation and data extraction. The effect of different input variables on the depth of anesthesia was studied by using a multi-data fusion approach. The results show that the data fusion algorithm proposed can effectively connect redundant information and complementary information in multiple data, and estimate the real parameters of the measured object. In addition, data fusion brings great convenience to the design of control algorithms and controllers, and provides an effective basis for system simplification. Experiments have shown that dexmedetomidine is effective and safe in the operation of neurosurgical motor function, and the management of the recovery period is safe and effective. Based on the research, it can provide some reference for the awakening of patients undergoing neurosurgery, and promote the progress and development of medicine. De Gruyter 2019-07-12 /pmc/articles/PMC6689226/ /pubmed/31410296 http://dx.doi.org/10.1515/tnsci-2019-0026 Text en © 2019 Jing Cao et al., published by De Gruyter http://creativecommons.org/licenses/by/4.0 This work is licensed under the Creative Commons Attribution 4.0 Public License.
spellingShingle Special Issue: Adult Neurogenesis and Neurological Disorders
Cao, Jing
Li, Hui
Song, Shengwen
Zhou, Xuyan
Shen, Xu
Analysis of Dexmedetomidine on the Quality of Awakening During Neurosurgery
title Analysis of Dexmedetomidine on the Quality of Awakening During Neurosurgery
title_full Analysis of Dexmedetomidine on the Quality of Awakening During Neurosurgery
title_fullStr Analysis of Dexmedetomidine on the Quality of Awakening During Neurosurgery
title_full_unstemmed Analysis of Dexmedetomidine on the Quality of Awakening During Neurosurgery
title_short Analysis of Dexmedetomidine on the Quality of Awakening During Neurosurgery
title_sort analysis of dexmedetomidine on the quality of awakening during neurosurgery
topic Special Issue: Adult Neurogenesis and Neurological Disorders
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689226/
https://www.ncbi.nlm.nih.gov/pubmed/31410296
http://dx.doi.org/10.1515/tnsci-2019-0026
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