Randomized Placebo-Controlled Trial Evaluating the Ophthalmic Safety of Single-Dose Tafenoquine in Healthy Volunteers

INTRODUCTION: Tafenoquine has been recently registered for the prevention of relapse in Plasmodium vivax malaria. OBJECTIVE: This study assessed the pharmacodynamic effects of 300-mg single-dose tafenoquine on the retina. METHODS: This phase I, prospective, multicenter, randomized, single-masked, pl...

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Detalles Bibliográficos
Autores principales: Ackert, Jessica, Mohamed, Khadeeja, Slakter, Jason S., El-Harazi, Sherif, Berni, Alessandro, Gevorkyan, Hakop, Hardaker, Elizabeth, Hussaini, Azra, Jones, Siôn W., Koh, Gavin C. K. W., Patel, Jyoti, Rasmussen, Scott, Kelly, Deborah S., Barañano, David E., Thompson, John T., Warren, Keith A., Sergott, Robert C., Tonkyn, John, Wolstenholme, Allen, Coleman, Hanna, Yuan, Alex, Duparc, Stephan, Green, Justin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689320/
https://www.ncbi.nlm.nih.gov/pubmed/31187437
http://dx.doi.org/10.1007/s40264-019-00839-w

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