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Deep Learning-Based Electrocardiogram Signal Noise Detection and Screening Model

OBJECTIVES: Biosignal data captured by patient monitoring systems could provide key evidence for detecting or predicting critical clinical events; however, noise in these data hinders their use. Because deep learning algorithms can extract features without human annotation, this study hypothesized t...

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Autores principales: Yoon, Dukyong, Lim, Hong Seok, Jung, Kyoungwon, Kim, Tae Young, Lee, Sukhoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Medical Informatics 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689506/
https://www.ncbi.nlm.nih.gov/pubmed/31406612
http://dx.doi.org/10.4258/hir.2019.25.3.201
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author Yoon, Dukyong
Lim, Hong Seok
Jung, Kyoungwon
Kim, Tae Young
Lee, Sukhoon
author_facet Yoon, Dukyong
Lim, Hong Seok
Jung, Kyoungwon
Kim, Tae Young
Lee, Sukhoon
author_sort Yoon, Dukyong
collection PubMed
description OBJECTIVES: Biosignal data captured by patient monitoring systems could provide key evidence for detecting or predicting critical clinical events; however, noise in these data hinders their use. Because deep learning algorithms can extract features without human annotation, this study hypothesized that they could be used to screen unacceptable electrocardiograms (ECGs) that include noise. To test that, a deep learning-based model for unacceptable ECG screening was developed, and its screening results were compared with the interpretations of a medical expert. METHODS: To develop and apply the screening model, we used a biosignal database comprising 165,142,920 ECG II (10-second lead II electrocardiogram) data gathered between August 31, 2016 and September 30, 2018 from a trauma intensive-care unit. Then, 2,700 and 300 ECGs (ratio of 9:1) were reviewed by a medical expert and used for 9-fold cross-validation (training and validation) and test datasets. A convolutional neural network-based model for unacceptable ECG screening was developed based on the training and validation datasets. The model exhibiting the lowest cross-validation loss was subsequently selected as the final model. Its performance was evaluated through comparison with a test dataset. RESULTS: When the screening results of the proposed model were compared to the test dataset, the area under the receiver operating characteristic curve and the F1-score of the model were 0.93 and 0.80 (sensitivity = 0.88, specificity = 0.89, positive predictive value = 0.74, and negative predictive value = 0.96). CONCLUSIONS: The deep learning-based model developed in this study is capable of detecting and screening unacceptable ECGs efficiently.
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spelling pubmed-66895062019-08-12 Deep Learning-Based Electrocardiogram Signal Noise Detection and Screening Model Yoon, Dukyong Lim, Hong Seok Jung, Kyoungwon Kim, Tae Young Lee, Sukhoon Healthc Inform Res Original Article OBJECTIVES: Biosignal data captured by patient monitoring systems could provide key evidence for detecting or predicting critical clinical events; however, noise in these data hinders their use. Because deep learning algorithms can extract features without human annotation, this study hypothesized that they could be used to screen unacceptable electrocardiograms (ECGs) that include noise. To test that, a deep learning-based model for unacceptable ECG screening was developed, and its screening results were compared with the interpretations of a medical expert. METHODS: To develop and apply the screening model, we used a biosignal database comprising 165,142,920 ECG II (10-second lead II electrocardiogram) data gathered between August 31, 2016 and September 30, 2018 from a trauma intensive-care unit. Then, 2,700 and 300 ECGs (ratio of 9:1) were reviewed by a medical expert and used for 9-fold cross-validation (training and validation) and test datasets. A convolutional neural network-based model for unacceptable ECG screening was developed based on the training and validation datasets. The model exhibiting the lowest cross-validation loss was subsequently selected as the final model. Its performance was evaluated through comparison with a test dataset. RESULTS: When the screening results of the proposed model were compared to the test dataset, the area under the receiver operating characteristic curve and the F1-score of the model were 0.93 and 0.80 (sensitivity = 0.88, specificity = 0.89, positive predictive value = 0.74, and negative predictive value = 0.96). CONCLUSIONS: The deep learning-based model developed in this study is capable of detecting and screening unacceptable ECGs efficiently. Korean Society of Medical Informatics 2019-07 2019-07-31 /pmc/articles/PMC6689506/ /pubmed/31406612 http://dx.doi.org/10.4258/hir.2019.25.3.201 Text en © 2019 The Korean Society of Medical Informatics http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Yoon, Dukyong
Lim, Hong Seok
Jung, Kyoungwon
Kim, Tae Young
Lee, Sukhoon
Deep Learning-Based Electrocardiogram Signal Noise Detection and Screening Model
title Deep Learning-Based Electrocardiogram Signal Noise Detection and Screening Model
title_full Deep Learning-Based Electrocardiogram Signal Noise Detection and Screening Model
title_fullStr Deep Learning-Based Electrocardiogram Signal Noise Detection and Screening Model
title_full_unstemmed Deep Learning-Based Electrocardiogram Signal Noise Detection and Screening Model
title_short Deep Learning-Based Electrocardiogram Signal Noise Detection and Screening Model
title_sort deep learning-based electrocardiogram signal noise detection and screening model
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689506/
https://www.ncbi.nlm.nih.gov/pubmed/31406612
http://dx.doi.org/10.4258/hir.2019.25.3.201
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