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Epigenetic mechanism controls PDK4 gene activation before and after exercise therapy following artificial knee arthroplasty

PURPOSE: DNA methylation is thought to play a role in exercise-induced gene expression. We aimed to examine changes in muscular strength and body composition in elderly patients with end-stage knee osteoarthritis before and after artificial knee arthroplasty and exercise therapy. We aimed to confirm...

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Detalles Bibliográficos
Autores principales: Kamo, Tomohiro, Kurose, Satoshi, Ohno, Hiroshi, Murata, Minoru, Hashiyada, Masaki, Saito, Takanori, Kimura, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689537/
https://www.ncbi.nlm.nih.gov/pubmed/31496670
http://dx.doi.org/10.2147/CIA.S213154