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Catalytic self-folding of 2D structures through cascading magnet reactions

While thousands of proteins involved in development of the human body are capable of self-assembling in a distributed manner from merely 20 types of amino acid, macroscopic products that can be assembled spontaneously from ‘alive’ components remains an aspiration in engineering. To attain such a mec...

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Autores principales: Southern, Emily J., Besnard, Valentin, Lahaye, Bastien, Tyrrell, Andy M., Miyashita, Shuhei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689604/
https://www.ncbi.nlm.nih.gov/pubmed/31417701
http://dx.doi.org/10.1098/rsos.182128
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author Southern, Emily J.
Besnard, Valentin
Lahaye, Bastien
Tyrrell, Andy M.
Miyashita, Shuhei
author_facet Southern, Emily J.
Besnard, Valentin
Lahaye, Bastien
Tyrrell, Andy M.
Miyashita, Shuhei
author_sort Southern, Emily J.
collection PubMed
description While thousands of proteins involved in development of the human body are capable of self-assembling in a distributed manner from merely 20 types of amino acid, macroscopic products that can be assembled spontaneously from ‘alive’ components remains an aspiration in engineering. To attain such a mechanism, a major challenge lies in understanding which attributes from the bio-molecular realm must be leveraged at the macro-scale. Inspired by protein folding, we present a centimetre-size 1D tile chain whose self-folding processes are directed by structure-embedded magnetic interactions, which can theoretically self-assemble into convex 2D structures of any size or shape without the aid of a global ‘controller’. Each tile holds two magnets contained in paths designed to control their interactions. Once initiated by a magnetic unit (termed Catalyst), the chain self-reconfigures by consuming magnetic potential energy stored between magnet pairs, until the final 2D structure is reached at an energetic minimum. Both simulation and experimental results are presented to illustrate the method’s efficacy on chains of arbitrary length. Results demonstrate the promise of a physically implemented, bottom-up, and scalable self-assembly method for novel 2D structure manufacturing, bridging the bio-molecular and mechanical realms.
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spelling pubmed-66896042019-08-15 Catalytic self-folding of 2D structures through cascading magnet reactions Southern, Emily J. Besnard, Valentin Lahaye, Bastien Tyrrell, Andy M. Miyashita, Shuhei R Soc Open Sci Engineering While thousands of proteins involved in development of the human body are capable of self-assembling in a distributed manner from merely 20 types of amino acid, macroscopic products that can be assembled spontaneously from ‘alive’ components remains an aspiration in engineering. To attain such a mechanism, a major challenge lies in understanding which attributes from the bio-molecular realm must be leveraged at the macro-scale. Inspired by protein folding, we present a centimetre-size 1D tile chain whose self-folding processes are directed by structure-embedded magnetic interactions, which can theoretically self-assemble into convex 2D structures of any size or shape without the aid of a global ‘controller’. Each tile holds two magnets contained in paths designed to control their interactions. Once initiated by a magnetic unit (termed Catalyst), the chain self-reconfigures by consuming magnetic potential energy stored between magnet pairs, until the final 2D structure is reached at an energetic minimum. Both simulation and experimental results are presented to illustrate the method’s efficacy on chains of arbitrary length. Results demonstrate the promise of a physically implemented, bottom-up, and scalable self-assembly method for novel 2D structure manufacturing, bridging the bio-molecular and mechanical realms. The Royal Society 2019-07-31 /pmc/articles/PMC6689604/ /pubmed/31417701 http://dx.doi.org/10.1098/rsos.182128 Text en © 2019 The Authors. http://creativecommons.org/licenses/by/4.0/ Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.
spellingShingle Engineering
Southern, Emily J.
Besnard, Valentin
Lahaye, Bastien
Tyrrell, Andy M.
Miyashita, Shuhei
Catalytic self-folding of 2D structures through cascading magnet reactions
title Catalytic self-folding of 2D structures through cascading magnet reactions
title_full Catalytic self-folding of 2D structures through cascading magnet reactions
title_fullStr Catalytic self-folding of 2D structures through cascading magnet reactions
title_full_unstemmed Catalytic self-folding of 2D structures through cascading magnet reactions
title_short Catalytic self-folding of 2D structures through cascading magnet reactions
title_sort catalytic self-folding of 2d structures through cascading magnet reactions
topic Engineering
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689604/
https://www.ncbi.nlm.nih.gov/pubmed/31417701
http://dx.doi.org/10.1098/rsos.182128
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