Cargando…
Clinical trial of a humanized anti‐IL‐2/IL‐15 receptor β chain in HAM/TSP
OBJECTIVE: Human T cell lymphotropic virus 1 (HTLV‐1)‐associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a chronic, progressive, neurological disease. Chronic activation of CD8(+) T cells, as evidenced by increased spontaneous lymphoproliferation and HTLV‐1‐specific cytotoxic T cells, h...
Autores principales: | Enose‐Akahata, Yoshimi, Oh, Unsong, Ohayon, Joan, Billioux, Bridgette Jeanne, Massoud, Raya, Bryant, Bonita R., Vellucci, Ashley, Ngouth, Nyater, Cortese, Irene, Waldmann, Thomas A., Jacobson, Steven |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689682/ https://www.ncbi.nlm.nih.gov/pubmed/31402625 http://dx.doi.org/10.1002/acn3.50820 |
Ejemplares similares
-
Clinical trial of raltegravir, an integrase inhibitor, in HAM/TSP
por: Enose‐Akahata, Yoshimi, et al.
Publicado: (2021) -
HTLV-1 epigenetic modification of the FoxP3 TSDR in HAM/TSP decreases the functional proliferative suppression of Tregs
por: Anderson, Monique R, et al.
Publicado: (2014) -
Clinical trial of a humanized monoclonal anti-IL15Rβ (CD122), in HTLV-1 associated myelopathy/ tropical spastic paraparesis (HAM/TSP)
por: Massoud, Raya, et al.
Publicado: (2014) -
Role of HTLV-1 Tax and HBZ in the Pathogenesis of HAM/TSP
por: Enose-Akahata, Yoshimi, et al.
Publicado: (2017) -
Immunophenotypic characterization of CSF B cells in virus-associated neuroinflammatory diseases
por: Enose-Akahata, Yoshimi, et al.
Publicado: (2018)