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Paclitaxel-loaded biodegradable ROS-sensitive nanoparticles for cancer therapy
BACKGROUND: Reactive oxygen species (ROS), such as hydrogen peroxide and superoxide, trigger biodegradation of polymer-based nanoparticles (NPs) bearing pinacol-type boronic ester groups. These NPs may selectively release their cargo, in this case paclitaxel (PTX), at the high levels of ROS present...
Autores principales: | Pandya, Abhilash D, Jäger, Eliézer, Bagheri Fam, Shahla, Höcherl, Anita, Jäger, Alessandro, Sincari, Vladimir, Nyström, Bo, Štěpánek, Petr, Skotland, Tore, Sandvig, Kirsten, Hrubý, Martin, Mælandsmo, Gunhild M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689768/ https://www.ncbi.nlm.nih.gov/pubmed/31496685 http://dx.doi.org/10.2147/IJN.S208938 |
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